Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AT689_RS00600 Genome accession   NZ_LN831051
Coordinates   118897..119586 (-) Length   229 a.a.
NCBI ID   WP_000518012.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 113897..124586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS13180 - 114648..114770 (-) 123 Protein_119 N-acetylmuramoyl-L-alanine amidase family protein -
  AT689_RS13185 - 114810..114977 (-) 168 Protein_120 transposase -
  AT689_RS12295 - 115640..115978 (+) 339 WP_001820155.1 lanthionine synthetase LanC family protein -
  AT689_RS12300 (ERS445053_00115) - 115878..116348 (+) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  AT689_RS00590 (ERS445053_00116) - 116507..117739 (+) 1233 WP_000765695.1 MFS transporter -
  AT689_RS00595 (ERS445053_00118) cbpC 117857..118799 (-) 943 Protein_124 choline-binding protein CbpC -
  AT689_RS00600 (ERS445053_00119) covR 118897..119586 (-) 690 WP_000518012.1 response regulator transcription factor Regulator
  AT689_RS00605 (ERS445053_00120) gndA 119598..121022 (-) 1425 WP_000158788.1 NADP-dependent phosphogluconate dehydrogenase -
  AT689_RS00610 (ERS445053_00121) mapZ 121098..122492 (-) 1395 WP_000039300.1 mid-cell-anchored protein MapZ -
  AT689_RS00615 (ERS445053_00122) - 122505..123662 (-) 1158 WP_000711387.1 class I SAM-dependent RNA methyltransferase -
  AT689_RS00625 (ERS445053_00124) gpsB 124148..124477 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26817.09 Da        Isoelectric Point: 6.9839

>NTDB_id=1114342 AT689_RS00600 WP_000518012.1 118897..119586(-) (covR) [Streptococcus pneumoniae strain NCTC7465]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVVIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSNIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1114342 AT689_RS00600 WP_000518012.1 118897..119586(-) (covR) [Streptococcus pneumoniae strain NCTC7465]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCGTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCAACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment