Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   LHA_RS06105 Genome accession   NZ_LN681225
Coordinates   1347221..1349437 (+) Length   738 a.a.
NCBI ID   WP_045105758.1    Uniprot ID   -
Organism   Legionella hackeliae strain ATCC 35250     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1342221..1354437
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LHA_RS06080 (LHA_1312) - 1342297..1342677 (-) 381 WP_045105753.1 hypothetical protein -
  LHA_RS06085 (LHA_1313) - 1342847..1344241 (-) 1395 WP_045105754.1 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta -
  LHA_RS06090 (LHA_1314) - 1344308..1344604 (-) 297 WP_045105755.1 proton-translocating transhydrogenase family protein -
  LHA_RS06095 (LHA_1315) - 1344597..1345721 (-) 1125 WP_045105756.1 Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha -
  LHA_RS06100 (LHA_1316) - 1345910..1347157 (+) 1248 WP_045105757.1 YopT-type cysteine protease domain-containing protein -
  LHA_RS06105 (LHA_1317) comEC 1347221..1349437 (+) 2217 WP_045105758.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LHA_RS06110 (LHA_1318) - 1349521..1350675 (+) 1155 WP_045105759.1 multidrug DMT transporter permease -
  LHA_RS06120 (LHA_1320) - 1351138..1352064 (+) 927 Protein_1200 F-box protein -
  LHA_RS17290 - 1352036..1352196 (-) 161 Protein_1201 IS256 family transposase -
  LHA_RS06125 (LHA_1322) - 1352224..1352754 (-) 531 WP_045105760.1 REP-associated tyrosine transposase -
  LHA_RS06130 (LHA_1324) - 1352938..1353417 (+) 480 WP_045105761.1 GNAT family N-acetyltransferase -
  LHA_RS16510 (LHA_1325) - 1353478..1353951 (-) 474 WP_197541150.1 REP-associated tyrosine transposase -

Sequence

Protein


Download         Length: 738 a.a.        Molecular weight: 83421.17 Da        Isoelectric Point: 9.8265

>NTDB_id=1113920 LHA_RS06105 WP_045105758.1 1347221..1349437(+) (comEC) [Legionella hackeliae strain ATCC 35250]
MEILCFFAGTAYFYSKSVYALLLVIFACILSPRWSFLIWFLAALLWATVHQWWIADLAMPNNTRVIPKARLEGEIVSIPN
TTDFKSQFQFRVSRFNGNAAQSTVLLACYNHCPSFNVGDFWDFEAKLKKPVNLGNPGSFDYVSWLNARHLEWTGYIKPHR
AKLLNRLHSQTLLSIREQLASSVVKLLPNEDSLGIVEALTLGLTSHIDKKQWDLFRRTGTTHLMVISGAHIGLVAGLSFA
LMRWLWTRSSRLCLYYPAAQPASILGLLMALVYALLAGFAAPAQRSLIACFFLLVKNFLNYRFTTWQAWRYGLLGVLLFE
PHDVLLPGFYLSFLAVASLLLGSQRLTMSGLKKSIGLQLICLFGLMPLTLFWFSYGAINGFFANLLAIPMVGFIIVPLAL
ISLFLVQCWDNSWILLPVHWAIEGLLYFLRWVDSFSQVNLSFSFNDILSPLALMLVMMLGLFLPLRALFPAMIVLSITAL
WPGFSKVKKGDAEINILDVGQGLAVLVQTANHRLVYDTGIKFYQGGDMAKLAIIPFLKTLGVKRIDKVIISHPDLDHRGG
LESLESTYLVDELLVNEVSFYHRGKNCHHYPSWQWDGVSFKFLAINKRFKNKNNNSCVLQVKNKKGRILLTGDIERLAED
FLVKAYKEQLASTVVVVPHHGSKTSSSLQFIQQIAPKFAIISAGFDNRYHFPHGQTLKTFERQKINVFNTAECGMVTVQL
FVKKDRVEPFCYKPIKSG

Nucleotide


Download         Length: 2217 bp        

>NTDB_id=1113920 LHA_RS06105 WP_045105758.1 1347221..1349437(+) (comEC) [Legionella hackeliae strain ATCC 35250]
ATGGAAATTCTCTGTTTTTTTGCAGGGACGGCTTACTTTTATTCAAAGTCAGTATATGCCCTTTTATTGGTAATTTTTGC
CTGTATTCTCTCCCCACGTTGGTCATTTCTTATTTGGTTTCTTGCCGCTCTATTGTGGGCTACTGTTCATCAATGGTGGA
TAGCGGATTTGGCTATGCCAAACAACACTCGTGTTATTCCAAAAGCTAGGTTGGAAGGAGAGATTGTATCCATTCCTAAC
ACAACGGATTTCAAATCCCAATTTCAATTTAGAGTTAGCCGTTTTAATGGAAACGCAGCGCAATCCACCGTATTACTCGC
TTGTTATAATCATTGTCCATCCTTCAATGTCGGAGACTTTTGGGATTTTGAAGCAAAATTAAAAAAACCAGTAAACTTGG
GAAATCCAGGAAGTTTTGATTATGTGAGTTGGTTAAATGCACGTCATTTGGAGTGGACTGGCTATATTAAACCGCATCGC
GCCAAACTTCTTAATCGTCTTCATTCACAAACTCTGTTAAGTATCCGCGAACAACTTGCTTCAAGCGTGGTTAAATTATT
ACCCAATGAAGACAGTTTGGGTATTGTTGAAGCATTAACGCTGGGCTTAACAAGCCATATCGACAAAAAGCAATGGGATC
TTTTTCGACGAACAGGAACCACGCATTTGATGGTGATTTCAGGGGCGCATATTGGGTTAGTAGCTGGATTAAGTTTTGCA
CTAATGCGTTGGCTTTGGACTCGAAGTAGCCGGTTATGCCTTTATTATCCTGCAGCACAGCCTGCAAGCATTCTGGGTTT
GTTAATGGCCCTGGTTTATGCGCTTTTGGCAGGATTTGCGGCTCCTGCACAACGCTCCTTAATTGCTTGTTTTTTTCTGC
TGGTTAAAAATTTTTTAAATTATCGTTTTACCACCTGGCAAGCCTGGCGTTATGGTTTATTGGGAGTGTTGTTATTTGAG
CCCCATGATGTTTTATTGCCCGGATTCTATTTATCTTTCTTAGCAGTCGCGAGTTTACTTCTAGGAAGTCAGCGCTTAAC
AATGTCAGGTTTAAAAAAAAGCATTGGCTTACAACTTATCTGTCTTTTTGGTTTGATGCCTTTGACCTTATTTTGGTTTT
CCTATGGGGCAATTAATGGATTTTTTGCCAATTTGTTAGCAATACCAATGGTTGGGTTTATTATTGTGCCTTTGGCGCTT
ATTAGTTTATTTTTGGTACAGTGTTGGGATAACTCCTGGATACTCCTGCCTGTACATTGGGCGATTGAAGGATTACTTTA
TTTTCTGCGATGGGTGGATTCGTTTTCGCAAGTTAATTTAAGTTTTTCTTTTAACGATATTTTATCCCCTTTAGCGTTAA
TGCTTGTGATGATGTTGGGGTTATTTCTACCATTAAGGGCATTATTTCCTGCCATGATTGTCTTGAGTATAACAGCGCTT
TGGCCCGGTTTTTCCAAAGTGAAAAAAGGGGATGCCGAAATCAATATTCTTGATGTGGGACAGGGATTGGCAGTCCTGGT
ACAAACCGCAAATCACAGGCTGGTTTATGATACGGGGATTAAGTTTTATCAGGGTGGGGATATGGCCAAATTGGCAATCA
TTCCCTTTCTTAAAACGCTTGGCGTTAAAAGGATTGACAAGGTAATAATTAGTCATCCTGATCTCGATCATCGTGGTGGC
TTGGAGTCTCTTGAGTCCACTTATCTTGTTGATGAACTTTTAGTGAATGAGGTTTCTTTTTATCATCGCGGAAAAAATTG
CCACCATTATCCTTCTTGGCAATGGGATGGGGTTTCCTTTAAGTTTTTAGCAATTAATAAGCGGTTTAAAAATAAGAATA
ATAATTCTTGTGTATTACAAGTTAAAAATAAGAAAGGTCGCATTTTACTCACTGGAGATATTGAGCGCCTGGCGGAGGAT
TTTTTGGTAAAAGCCTACAAAGAACAACTTGCCTCAACCGTTGTTGTGGTACCTCATCATGGCAGTAAAACATCGTCATC
GTTACAATTTATCCAGCAAATTGCACCAAAGTTTGCGATTATTTCAGCAGGTTTTGACAATCGTTACCATTTTCCCCATG
GGCAAACCCTGAAAACCTTTGAGCGGCAAAAGATTAACGTATTTAATACGGCGGAGTGTGGCATGGTCACTGTACAGTTG
TTCGTAAAAAAAGACAGGGTTGAACCATTTTGTTATAAACCCATTAAGAGTGGGTAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(20-158)

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-582)

Competence protein (Competence)

(199-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain Lp02

48.575

99.864

0.485
  comEC Legionella pneumophila strain ERS1305867

48.571

99.593

0.484

Multiple sequence alignment