Detailed information NTG1113815

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: VV34_RS19395
• Genome accession: NZ_LN649259
• Coordinates: 3681424..3682581 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain BS49
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3676424..3687581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VV34_RS19365 (BS49_38720)	yvyF	3676677..3677096 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
VV34_RS19370 (BS49_38730)	comFC	3677170..3677892 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
VV34_RS19375 (BS49_38740)	comFB	3677856..3678152 (-)	297	WP_003227989.1	late competence protein ComFB	-
VV34_RS19380 (BS49_38750)	comFA	3678212..3679603 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
VV34_RS19385 (BS49_38760)	fakBA	3679709..3680554 (-)	846	WP_003244125.1	DegV family protein	-
VV34_RS19390 (BS49_38770)	degU	3680652..3681341 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
VV34_RS19395 (BS49_38780)	degS	3681424..3682581 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
VV34_RS19400 (BS49_38790)	yvyE	3682798..3683451 (+)	654	WP_003227979.1	YigZ family protein	-
VV34_RS19405 (BS49_38800)	tagV	3683451..3684626 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
VV34_RS19410 (BS49_38810)	tagO	3684699..3685775 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
VV34_RS19415 (BS49_38820)	tuaH	3685920..3687113 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=1113815 VV34_RS19395 WP_003227983.1 3681424..3682581(-) (degS) [Bacillus subtilis strain BS49]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=1113815 VV34_RS19395 WP_003227983.1 3681424..3682581(-) (degS) [Bacillus subtilis strain BS49]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1