Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   SRS_RS08485 Genome accession   NZ_LN626917
Coordinates   1682355..1683041 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1677355..1688041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRS_RS08465 rpsT 1678269..1678520 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  SRS_RS08470 holA 1678565..1679539 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  SRS_RS08475 comEC 1679596..1681797 (-) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SRS_RS08480 - 1681802..1682263 (-) 462 WP_000439692.1 ComE operon protein 2 -
  SRS_RS08485 comEA 1682355..1683041 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  SRS_RS08490 - 1683081..1683797 (-) 717 WP_000084835.1 class I SAM-dependent DNA methyltransferase -
  SRS_RS08495 rsfS 1683800..1684153 (-) 354 WP_001088020.1 ribosome silencing factor -
  SRS_RS08500 yqeK 1684154..1684738 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  SRS_RS08505 nadD 1684728..1685297 (-) 570 WP_045179209.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  SRS_RS08510 yhbY 1685300..1685590 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  SRS_RS08515 aroE 1685594..1686400 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  SRS_RS08520 yqeH 1686414..1687514 (-) 1101 WP_001280133.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=1113692 SRS_RS08485 WP_001794049.1 1682355..1683041(-) (comEA) [Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1113692 SRS_RS08485 WP_001794049.1 1682355..1683041(-) (comEA) [Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952

Multiple sequence alignment