Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   SRS_RS08260 Genome accession   NZ_LN626917
Coordinates   1637536..1638510 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1632536..1643510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRS_RS08220 gcvT 1633037..1634128 (-) 1092 WP_045179191.1 glycine cleavage system aminomethyltransferase GcvT -
  SRS_RS08225 - 1634287..1634811 (-) 525 WP_001015125.1 shikimate kinase -
  SRS_RS08230 - 1634801..1634947 (-) 147 WP_001789879.1 hypothetical protein -
  SRS_RS08235 comGF 1635044..1635541 (-) 498 WP_001794328.1 competence type IV pilus minor pilin ComGF Machinery gene
  SRS_RS08240 comGE 1635459..1635758 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  SRS_RS08245 comGD 1635745..1636191 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  SRS_RS08250 comGC 1636169..1636480 (-) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  SRS_RS08255 comGB 1636494..1637564 (-) 1071 WP_000776412.1 competence type IV pilus assembly protein ComGB Machinery gene
  SRS_RS08260 comGA 1637536..1638510 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  SRS_RS08265 - 1638562..1639185 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  SRS_RS08270 - 1639182..1639511 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  SRS_RS08275 - 1639511..1640497 (-) 987 WP_000161314.1 ROK family glucokinase -
  SRS_RS08280 - 1640494..1640697 (-) 204 WP_000087561.1 YqgQ family protein -
  SRS_RS08285 - 1640678..1642141 (-) 1464 WP_045179195.1 rhomboid family protein -
  SRS_RS08290 - 1642153..1642692 (-) 540 WP_000164553.1 5-formyltetrahydrofolate cyclo-ligase -
  SRS_RS08295 rpmG 1642901..1643050 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=1113689 SRS_RS08260 WP_000697220.1 1637536..1638510(-) (comGA) [Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=1113689 SRS_RS08260 WP_000697220.1 1637536..1638510(-) (comGA) [Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTGCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment