Detailed information NTG1113653

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: LMI_RS11220
• Genome accession: NZ_LN614830
• Coordinates: 2520726..2523464 (+)
• Length: 912 a.a.
• NCBI ID: WP_045099878.1
• Uniprot ID: A0A098GI65
• Organism: Legionella micdadei strain ATCC 33218
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2515726..2528464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LMI_RS11205 (LMI_2409)	-	2516871..2518424 (+)	1554	WP_052679550.1	PAS domain-containing sensor histidine kinase	-
LMI_RS11210 (LMI_2410)	-	2518630..2519028 (+)	399	WP_052679551.1	response regulator	-
LMI_RS11215 (LMI_2411)	gltX	2519147..2520568 (-)	1422	WP_045099877.1	glutamate--tRNA ligase	-
LMI_RS11220 (LMI_2412)	letS	2520726..2523464 (+)	2739	WP_045099878.1	two-component system sensor histidine kinase LetS	Regulator
LMI_RS11225 (LMI_2413)	-	2523487..2524722 (+)	1236	WP_045100733.1	6-phosphofructokinase	-
LMI_RS11230 (LMI_2415)	-	2524813..2525157 (-)	345	WP_052679552.1	hypothetical protein	-
LMI_RS11235 (LMI_2417)	-	2525359..2526540 (-)	1182	WP_045099879.1	cupin domain-containing protein	-
LMI_RS11240 (LMI_2418)	-	2526721..2528079 (-)	1359	WP_045099880.1	TcdA/TcdB catalytic glycosyltransferase domain-containing protein	-

Sequence

Protein

• Length: 912 a.a.
• Molecular weight: 102738.78 Da
• Isoelectric Point: 7.0975

>NTDB_id=1113653 LMI_RS11220 WP_045099878.1 2520726..2523464(+) (letS) [Legionella micdadei strain ATCC 33218]
MKRLGIKYQLRITTLIPVLLVALLFAVFFNGQFNKDLNQHMSRLGEAYIRQLLPAAQFAMLRNDSRTLQGLINASTVNPE
VKALAFYNAQGQLLAYRGGKHSIHKPFKPPEFTGDYIESKQIKPYTINFTAPITIPKFNLYSTTPFKALTNPIALQADDI
LGWLSLDIDTQSMLIMQYRMYIVTIFIILLGLLMSLTIHYFLSKRIYLPISRLRRSMKQILSNEFETHINVSSPGELGII
ERGCAHLQRQYLNIVNDLNHHIEVATADLQQSLELLEEKNIELSLEKKKAEEKSRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDSLQLDYVKTIKSSAQDLLAIINDILDYSKMDAGKLHLDCIPLDIRACIDEVLALTAPNAHKKGVDLIPSTAV
NVPKTVPGDPLRIKQIITNLVSNAVKFTDRGYVLIRTTIEQETEKDYTLCISVTDTGIGISGEDQTKLFNAFNQADTTIT
RRYGGSGLGLVICKKLVETMQGRITLTSEVNKGSTFAVRIKLEKLAAYEVEKHQSQRFDNLKALCYDDNPLYLEALCNGL
GYWGIETVPVSSFNQLEAAFAKHSDCTLAFINVNEGCEKQIAQTLRKQSISCVLISKWLIHDPQALGAQAFLFKPISIQK
LHETIEFLLNQASQTPATDHELDNLRSQLRIAHPELLIAEDNPVNRMLLNSLLSEHTNIETVDNGEEAVKACQSKRYNVI
LLDLQMPKINGLDAARLIRQESMLNKQTPIVVISANSSDLNKERLEKSGVDLCLQKPIDEKQLLNHLLLFLKKSKPAAID
WQLCVQKVSGNQALAEEFLARFVDELHKNREEFLQLLHDKNIKGLESAAHKLHGACCFCGVPHLQTQVIQLEKLAKRAKN
IEELKPAFTELIKSIDEVIDEFNDLYQTNSSD

Nucleotide

• Length: 2739 bp

>NTDB_id=1113653 LMI_RS11220 WP_045099878.1 2520726..2523464(+) (letS) [Legionella micdadei strain ATCC 33218]
ATGAAAAGACTCGGCATCAAATACCAGCTGCGCATCACTACGTTAATACCAGTACTTTTGGTCGCCCTCCTCTTTGCCGT
ATTCTTTAATGGCCAATTTAATAAAGATTTAAATCAGCACATGTCACGTTTAGGTGAAGCATATATTCGCCAATTATTAC
CCGCTGCCCAATTCGCAATGTTGCGCAACGATAGTCGAACATTGCAAGGTTTAATCAATGCGTCAACAGTGAATCCCGAG
GTCAAGGCCTTGGCCTTTTACAACGCCCAGGGACAATTGCTTGCGTATCGGGGGGGCAAACATTCCATTCATAAGCCTTT
TAAACCACCGGAATTCACTGGTGATTATATTGAGAGCAAGCAAATCAAACCTTACACAATTAATTTCACTGCTCCTATCA
CCATTCCTAAGTTTAATCTTTATTCAACCACGCCCTTTAAAGCACTAACTAACCCTATTGCCTTGCAAGCCGATGATATT
TTAGGTTGGCTTTCCCTTGATATTGACACGCAATCAATGCTTATCATGCAATATCGCATGTATATCGTGACCATTTTCAT
TATTTTGCTTGGCTTGCTAATGAGTTTAACCATCCATTATTTCTTATCCAAGCGAATCTACCTGCCTATTTCTCGTCTTA
GACGCAGTATGAAACAAATCTTAAGTAATGAATTTGAAACGCACATTAATGTCTCAAGCCCAGGTGAATTAGGCATTATT
GAGCGGGGTTGCGCCCATTTACAAAGACAGTACTTAAATATTGTTAATGATTTAAATCATCACATCGAAGTTGCAACCGC
AGACTTGCAGCAAAGCTTAGAATTATTGGAAGAGAAAAATATTGAACTCTCATTAGAGAAGAAAAAAGCAGAGGAAAAAA
GCAGGCAAAAATCAGAGTTTATTGCCAACATGAGTCATGAAATTCGCACCCCAATGAATGGGGTAATCGGATTTACTAAC
GTCTTACTCGAATCAAAATTAGATAGTCTGCAGCTTGATTACGTCAAAACAATTAAATCCTCTGCGCAAGATTTATTGGC
CATCATTAACGATATTCTCGATTACTCTAAAATGGATGCCGGCAAATTGCATTTGGATTGTATACCCCTCGACATTCGTG
CCTGCATCGATGAGGTATTAGCCCTCACTGCGCCTAATGCCCACAAAAAAGGAGTCGATTTAATCCCTTCAACGGCCGTA
AATGTACCTAAAACAGTACCGGGCGATCCTTTGCGTATTAAACAGATTATTACCAATCTAGTCAGCAATGCCGTTAAGTT
TACCGATCGAGGCTACGTGCTTATCCGTACTACGATTGAACAAGAGACGGAAAAGGATTATACGCTCTGTATCTCGGTTA
CCGACACTGGGATTGGCATTTCCGGTGAAGATCAAACCAAATTATTTAATGCATTTAACCAAGCAGACACAACAATCACC
CGTCGCTACGGCGGGTCTGGCTTAGGCTTAGTCATCTGCAAAAAATTAGTTGAAACCATGCAGGGACGAATAACCCTAAC
AAGTGAAGTGAATAAAGGATCAACTTTTGCGGTACGAATCAAACTTGAAAAATTAGCTGCTTATGAAGTTGAAAAGCATC
AAAGCCAGCGTTTCGATAATCTAAAAGCCCTTTGTTATGATGACAATCCCCTATATTTAGAGGCCCTGTGTAATGGATTA
GGTTACTGGGGTATTGAAACTGTCCCTGTCAGTTCCTTTAATCAACTTGAAGCAGCCTTTGCTAAACACAGCGATTGCAC
GCTTGCCTTCATTAACGTGAATGAAGGTTGTGAAAAACAAATAGCTCAGACATTACGCAAACAGTCCATTTCTTGCGTGC
TGATTTCTAAATGGCTTATCCATGATCCTCAAGCACTTGGCGCCCAGGCCTTCTTGTTCAAACCAATTAGTATTCAAAAA
CTGCATGAGACCATTGAATTTTTACTCAACCAAGCCTCGCAAACCCCTGCAACAGATCATGAACTAGACAACCTGCGGTC
TCAACTTCGTATCGCCCATCCTGAATTGTTAATTGCAGAAGATAATCCAGTCAATCGCATGTTACTCAATTCGCTACTCA
GCGAACACACAAATATTGAAACCGTGGATAATGGGGAGGAAGCAGTAAAAGCCTGTCAGAGTAAACGGTACAATGTCATT
TTGCTTGATTTACAAATGCCCAAAATCAATGGACTCGATGCAGCACGCTTGATTCGCCAGGAATCCATGTTGAATAAGCA
AACTCCAATTGTCGTCATCAGTGCAAATAGTTCGGATTTAAATAAAGAGCGGTTAGAAAAATCAGGTGTTGATCTCTGCT
TGCAAAAGCCCATTGATGAAAAACAACTTCTTAACCATCTTTTGCTCTTTCTAAAAAAATCAAAACCAGCAGCCATTGAT
TGGCAGCTCTGCGTGCAAAAAGTTTCAGGAAATCAAGCTCTAGCTGAGGAATTTCTTGCTCGTTTCGTTGATGAATTACA
CAAAAATCGAGAAGAGTTCCTGCAATTATTACATGATAAAAACATCAAAGGATTGGAAAGTGCCGCCCATAAATTACATG
GTGCTTGTTGTTTCTGTGGTGTACCCCATTTACAAACCCAAGTTATCCAGCTTGAAAAACTAGCTAAGCGCGCAAAAAAT
ATCGAAGAATTAAAACCAGCGTTTACCGAACTTATTAAAAGTATTGATGAGGTTATTGATGAATTTAATGATCTCTATCA
AACTAATTCCTCTGACTAA

Domains

Predicted by InterproScan.

• Hpt domain (Hpt) (817-898)

• Single cache domain 4 (sCache_4) (35-179)

• Response regulator receiver domain (Response_reg) (677-787)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-524)

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

3D structure

• AlphaFold DB: A0A098GI65

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	74.862	99.452	0.745