Detailed information NTG1113550

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SXYL_RS04675
• Genome accession: NZ_LN554884
• Coordinates: 1009077..1010120 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain C2a
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1004077..1015120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SXYL_RS04650 (SXYL_00946)	-	1005031..1005753 (+)	723	WP_042362406.1	type 1 glutamine amidotransferase	-
SXYL_RS04655 (SXYL_00947)	-	1005956..1006942 (-)	987	WP_042362407.1	FUSC family protein	-
SXYL_RS04660 (SXYL_00948)	map	1007119..1007871 (+)	753	WP_039069016.1	type I methionyl aminopeptidase	-
SXYL_RS04665 (SXYL_00949)	-	1007976..1008362 (+)	387	WP_042362408.1	hypothetical protein	-
SXYL_RS04670 (SXYL_00950)	liaF	1008379..1009080 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
SXYL_RS04675 (SXYL_00951)	vraS	1009077..1010120 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
SXYL_RS04680 (SXYL_00952)	vraR	1010110..1010739 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
SXYL_RS04685 (SXYL_00953)	-	1011008..1012153 (-)	1146	WP_042362411.1	YihY/virulence factor BrkB family protein	-
SXYL_RS04690 (SXYL_00954)	-	1012509..1012793 (-)	285	WP_042362412.1	hypothetical protein	-
SXYL_RS04695 (SXYL_00955)	-	1012800..1013264 (-)	465	WP_029378983.1	low molecular weight protein-tyrosine-phosphatase	-
SXYL_RS04700 (SXYL_00956)	-	1013399..1013602 (+)	204	WP_017723498.1	DUF1128 family protein	-
SXYL_RS04705 (SXYL_00957)	-	1013620..1014858 (+)	1239	WP_047172144.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=1113550 SXYL_RS04675 WP_042362410.1 1009077..1010120(+) (vraS) [Staphylococcus xylosus strain C2a]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=1113550 SXYL_RS04675 WP_042362410.1 1009077..1010120(+) (vraS) [Staphylococcus xylosus strain C2a]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTAGCACGTGAATTACATGATTCAGTGAGT
CAGCAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAGGCACCACTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGACTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACAAAAGTAACTATAGAGTTATTTAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTACCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885