Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   SPYH293_RS09185 Genome accession   NZ_HG316453
Coordinates   54078..54173 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain H293     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 49078..59173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYH293_RS00310 (SPYH293_00065) purK 49148..50221 (+) 1074 WP_023611330.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SPYH293_RS00315 (SPYH293_00066) - 50223..51641 (+) 1419 WP_023612101.1 hypothetical protein -
  SPYH293_RS00320 (SPYH293_00067) purB 51661..52953 (+) 1293 WP_023612104.1 adenylosuccinate lyase -
  SPYH293_RS00325 (SPYH293_00068) comR 53083..53994 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  SPYH293_RS09185 comS 54078..54173 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  SPYH293_RS00330 (SPYH293_00069) ruvB 54220..55218 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  SPYH293_RS00335 (SPYH293_00070) - 55356..55793 (+) 438 WP_020904819.1 low molecular weight protein-tyrosine-phosphatase -
  SPYH293_RS00340 (SPYH293_00071) - 55817..56218 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  SPYH293_RS00345 (SPYH293_00072) - 56215..57990 (+) 1776 WP_014407199.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=1111891 SPYH293_RS09185 WP_198462994.1 54078..54173(+) (comS) [Streptococcus pyogenes strain H293]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=1111891 SPYH293_RS09185 WP_198462994.1 54078..54173(+) (comS) [Streptococcus pyogenes strain H293]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452


Multiple sequence alignment