Detailed information NTG1111868

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SPYH293_RS03420
• Genome accession: NZ_HG316453
• Coordinates: 684503..685732 (+)
• Length: 409 a.a.
• NCBI ID: WP_053039050.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain H293
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 679503..690732

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYH293_RS03400 (SPYH293_00700)	-	680119..681396 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
SPYH293_RS03405 (SPYH293_00701)	-	681383..682558 (-)	1176	WP_031488354.1	hydroxymethylglutaryl-CoA synthase	-
SPYH293_RS03410 (SPYH293_00702)	-	682767..683606 (+)	840	WP_011017679.1	thymidylate synthase	-
SPYH293_RS03415 (SPYH293_00703)	-	683686..684183 (+)	498	WP_031488353.1	dihydrofolate reductase	-
SPYH293_RS03420 (SPYH293_00705)	clpX	684503..685732 (+)	1230	WP_053039050.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SPYH293_RS03425 (SPYH293_00706)	yihA	685742..686341 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SPYH293_RS03430 (SPYH293_00707)	-	686489..687232 (+)	744	WP_002984942.1	hypothetical protein	-
SPYH293_RS03435 (SPYH293_00708)	-	687290..689389 (-)	2100	WP_031488351.1	AAA family ATPase	-
SPYH293_RS03440 (SPYH293_00709)	rpiA	689767..690450 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44957.46 Da
• Isoelectric Point: 4.6184

>NTDB_id=1111868 SPYH293_RS03420 WP_053039050.1 684503..685732(+) (clpX) [Streptococcus pyogenes strain H293]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSLTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1111868 SPYH293_RS03420 WP_053039050.1 684503..685732(+) (clpX) [Streptococcus pyogenes strain H293]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGTCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTTTCGCTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTAAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575