Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   HMPREF9425_RS07340 Genome accession   NZ_GL831112
Coordinates   1522549..1523868 (-) Length   439 a.a.
NCBI ID   WP_003097890.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1517549..1528868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS07320 (HMPREF9425_1534) - 1517883..1518815 (-) 933 WP_003097884.1 manganese-dependent inorganic pyrophosphatase -
  HMPREF9425_RS07330 (HMPREF9425_1535) hpf 1521279..1521827 (-) 549 WP_003097886.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  HMPREF9425_RS07335 (HMPREF9425_1536) - 1521906..1522568 (-) 663 WP_003097888.1 ComF family protein -
  HMPREF9425_RS07340 (HMPREF9425_1537) comFA/cflA 1522549..1523868 (-) 1320 WP_003097890.1 DEAD/DEAH box helicase Machinery gene
  HMPREF9425_RS07345 (HMPREF9425_1538) - 1523923..1524549 (+) 627 WP_003097893.1 YigZ family protein -
  HMPREF9425_RS07350 (HMPREF9425_1539) cysK 1524651..1525577 (+) 927 WP_003097895.1 cysteine synthase A -
  HMPREF9425_RS07355 (HMPREF9425_1540) - 1525742..1526401 (-) 660 WP_003097896.1 CBS and ACT domain-containing protein -
  HMPREF9425_RS07360 (HMPREF9425_1541) - 1526536..1527246 (-) 711 WP_003093126.1 ABC transporter ATP-binding protein -
  HMPREF9425_RS07365 (HMPREF9425_1542) - 1527246..1528010 (-) 765 WP_003093115.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50484.77 Da        Isoelectric Point: 9.8665

>NTDB_id=1111761 HMPREF9425_RS07340 WP_003097890.1 1522549..1523868(-) (comFA/cflA) [Streptococcus vestibularis ATCC 49124]
MIPKEYYGRLFTKAQLPVDYLSEAVKLESMIKVDKKLRCKRCYSQIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWLGKLTPYQNEVSEKLLKTYKNKKHSLVHAVTGAGKTEMIYKIVAYVLENKNRVAIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGALEKHHLARRFHGNPLVLPRFFWQGRLQKSLTNGKLPSLLIHQIKKQRKSNFPLLIFFPNIAVGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1111761 HMPREF9425_RS07340 WP_003097890.1 1522549..1523868(-) (comFA/cflA) [Streptococcus vestibularis ATCC 49124]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGCACAGTTACCAGTGGACTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCAAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGTAAAGAACTCTATTACTTTCCTTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTTAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAACAAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGTAAGACAGAGATGATTTATAAGATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGCCATTGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGT
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGTTTTGACTTGATTATTGTTGACGAAGTTGATGCCTTCCCCTTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAAGCAAAGACGGAAACAGGTCGATATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAGGAGCAAGTTCGCCTTGGAGCTTTAGAAAAGCATCACCTTGCCAGACGCTTCCATGGAAATCCTTTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAACGGCAAGCTCCCAAGCCTTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTTCCCAATATAGCAGTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATACCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGTGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAACTGTCAATCTTAGTGACAACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAGGAGGCTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae D39

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae R6

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae TIGR4

55.452

98.178

0.544
  comFA/cflA Streptococcus mitis NCTC 12261

55.116

97.95

0.54
  comFA/cflA Streptococcus mitis SK321

54.186

97.95

0.531
  comFA Lactococcus lactis subsp. cremoris KW2

45.952

95.672

0.44
  comFA Latilactobacillus sakei subsp. sakei 23K

37.011

99.089

0.367

Multiple sequence alignment