Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   HMPREF9425_RS06330 Genome accession   NZ_GL831112
Coordinates   1289728..1291998 (+) Length   756 a.a.
NCBI ID   WP_003094803.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1284728..1296998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS06305 (HMPREF9425_1323) - 1285876..1286352 (-) 477 WP_003094204.1 ferrous iron transport protein A -
  HMPREF9425_RS06310 (HMPREF9425_1324) - 1286525..1287259 (-) 735 WP_003094046.1 amino acid ABC transporter ATP-binding protein -
  HMPREF9425_RS06315 (HMPREF9425_1325) - 1287259..1287939 (-) 681 WP_002886081.1 amino acid ABC transporter permease -
  HMPREF9425_RS06320 (HMPREF9425_1326) - 1288207..1288437 (-) 231 WP_002885970.1 DUF1797 family protein -
  HMPREF9425_RS06325 (HMPREF9425_1327) argF 1288506..1289486 (-) 981 WP_003097591.1 ornithine carbamoyltransferase -
  HMPREF9425_RS06330 (HMPREF9425_1328) clpE 1289728..1291998 (+) 2271 WP_003094803.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  HMPREF9425_RS06335 (HMPREF9425_1329) - 1292141..1292605 (+) 465 WP_003094661.1 NUDIX hydrolase -
  HMPREF9425_RS06340 (HMPREF9425_1330) - 1292602..1292904 (+) 303 WP_002885967.1 DUF1827 family protein -
  HMPREF9425_RS06345 (HMPREF9425_1331) - 1292944..1293906 (-) 963 WP_003097594.1 Gfo/Idh/MocA family protein -
  HMPREF9425_RS06350 (HMPREF9425_1332) - 1294006..1295241 (-) 1236 WP_003097596.1 aminoacyltransferase -
  HMPREF9425_RS06355 (HMPREF9425_1333) - 1295219..1295728 (-) 510 WP_003093909.1 TVP38/TMEM64 family protein -
  HMPREF9425_RS06360 (HMPREF9425_1334) - 1295974..1296594 (-) 621 WP_003097599.1 DUF3862 domain-containing protein -

Sequence

Protein


Download         Length: 756 a.a.        Molecular weight: 84158.32 Da        Isoelectric Point: 5.2166

>NTDB_id=1111754 HMPREF9425_RS06330 WP_003094803.1 1289728..1291998(+) (clpE) [Streptococcus vestibularis ATCC 49124]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPKNPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGNTQGPGRPEGPRQQATQQPQGLLEEFGINITNIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGNVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKNIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPVITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGATRENRTNSVLNQLGDFFSPEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQRLANNGIHLSVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKVEKNTQKAEAAKESD

Nucleotide


Download         Length: 2271 bp        

>NTDB_id=1111754 HMPREF9425_RS06330 WP_003094803.1 1289728..1291998(+) (clpE) [Streptococcus vestibularis ATCC 49124]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTATATACCAATGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGACCCCAAAAACCCCCTCAATCAATTCAATCAAACAGGAGGTTCCA
ACTTCTTCGATGATTTCTTCAGCGACCTAAATAATTTCCGTTCTTCTAACGGTGATCTTCCCAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAACGGTGGCAATACACAAGGGCCAGGCCGTCCAGAAGGACCACGCCAACAAGCTACTCAACA
ACCTCAAGGCCTTCTTGAAGAATTTGGAATTAATATCACAAATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAATCCTGTTCTCATCGGTGAGCCTGGT
GTTGGTAAAACCGCTGTAGTCGAAGGACTTGCCCAAAAAATTGTTGACGGTAATGTGCCACAAAAACTCCAAGGCAAGCA
AGTGATCCGTCTTGATGTGGTCAGCCTGGTTCAAGGGACTGGTATCCGTGGCCAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTCTTTATTGACGAAATCCATGAAATTGTAGGAGCTGGTAATGCTGGG
GATGGCAATATGGATGCTGGAAATATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACT
CAACGAATACCGTATCATTGAGAAAGATGCTGCACTCGAACGTCGTATGCAACCCGTTAAGGTAGATGAGCCAACAGTTG
AGGAAACAATCACAATTTTGCGTGGTATTCAGCCTAAATATCAAGACTACCACCACGTCAAATATACGGACGAAGCGATT
ACTGCAGCTGCAGAATTGTCCAACCGCTACATTCAAGACCGCTTCTTGCCAGACAAGGCCATCGACCTTCTGGATGAAGC
TGGTTCGAAGATGAACTTGACCCTCAACTTTATCGATCCTAAGAACATCGATAAACGTTTGATTGAAGCAGAGAATCTTA
AAGCTCAGGCTACTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCCAAATACAAGGAAATGCAA
AAGCAAACCATCAAAGACCAGGATATGCCTGTCATCACCGAAAAACATATCGAAGCTATTGTGGAACAAAAGACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCCGATGATCTTAAATCACATGTTATCGGAC
AAGATGCTGCAGTTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGATTGGGTGCTCCAAACCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAATTGGCTATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTTGGTGCCCCTCCAGGAT
ATGTTGGTTACGACGAAGCTGGTCAGTTGACTGAAAAAGTCCGCCGTAATCCTTATTCACTTATTCTTTTAGATGAGGTT
GAAAAAGCTCACCCAGACGTTCTTCACATGTTCCTCCAAGTACTCGACGACGGTCGTTTGACTGATGGTCAAGGGCGCAC
TGTAAGCTTCAAGGATACCATCATCATCATGACATCAAATGCTGGTACTGGTAAAGTTGAAGCTAGCGTTGGCTTTGGAG
CTACTCGTGAAAATCGTACCAATTCTGTTCTTAACCAACTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGCTTTGAC
GGTATTATCGAATTCTCTGCCCTTAGCAAAGAAAATCTCCTTACTATCGTGGACCTCATGCTTGATAATGTCAACCAACG
CTTGGCTAACAACGGTATCCACCTCAGTGTAACAGAGAAAGTTAAGGAAAAATTGGTTGACCTTGGTTACGATCCTAAGA
TGGGTGCTCGACCACTACGTCGTACCATCCAGGACCATATTGAAGATGCCATTACCGACTTCTACCTTGAAAATCCAAAC
GAAAAAGATCTCAAGGCAGTCATGACTTCAAAAGGCCACATTACCATTAAGTCTGCTAAAAAAGTCGAAAAAAATACTCA
AAAAGCTGAGGCAGCAAAAGAATCTGATTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(154-274)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-721)

AAA lid domain (AAA_lid_9)

(292-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.505

99.471

0.851
  clpE Streptococcus pneumoniae Rx1

82.603

99.603

0.823
  clpE Streptococcus pneumoniae D39

82.603

99.603

0.823
  clpE Streptococcus pneumoniae R6

82.603

99.603

0.823
  clpE Streptococcus pneumoniae TIGR4

82.603

99.603

0.823
  clpC Lactococcus lactis subsp. cremoris KW2

78.445

96.958

0.761
  clpC Bacillus subtilis subsp. subtilis str. 168

51.852

85.714

0.444
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.037

86.772

0.399
  clpC Streptococcus pneumoniae Rx1

47.36

82.672

0.392
  clpC Streptococcus pneumoniae D39

47.36

82.672

0.392
  clpC Streptococcus thermophilus LMD-9

47.267

82.275

0.389
  clpC Streptococcus pneumoniae TIGR4

47.04

82.672

0.389
  clpC Streptococcus thermophilus LMG 18311

46.945

82.275

0.386
  clpC Streptococcus mutans UA159

46.504

81.349

0.378

Multiple sequence alignment