Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACN076_RS03115 Genome accession   NZ_CP184836
Coordinates   626488..627177 (+) Length   229 a.a.
NCBI ID   WP_050283620.1    Uniprot ID   A0A1E9GD25
Organism   Streptococcus sp. K0074     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 621488..632177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS03090 (ACN076_03090) gpsB 621594..621923 (+) 330 WP_420790100.1 cell division regulator GpsB -
  ACN076_RS03100 (ACN076_03100) - 622409..623566 (+) 1158 WP_101781606.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  ACN076_RS03105 (ACN076_03105) mapZ 623579..624976 (+) 1398 WP_420790101.1 cell division site-positioning protein MapZ -
  ACN076_RS03110 (ACN076_03110) gndA 625052..626476 (+) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  ACN076_RS03115 (ACN076_03115) covR 626488..627177 (+) 690 WP_050283620.1 response regulator transcription factor Regulator
  ACN076_RS03120 (ACN076_03120) - 627277..628251 (+) 975 WP_420790102.1 N-acetylmuramoyl-L-alanine amidase family protein -
  ACN076_RS03125 (ACN076_03125) mvk 628374..629252 (+) 879 WP_261045137.1 mevalonate kinase -
  ACN076_RS03130 (ACN076_03130) mvaD 629234..630187 (+) 954 WP_420790103.1 diphosphomevalonate decarboxylase -
  ACN076_RS03135 (ACN076_03135) - 630174..631181 (+) 1008 WP_420790104.1 phosphomevalonate kinase -
  ACN076_RS03140 (ACN076_03140) fni 631165..632175 (+) 1011 WP_420790105.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26766.86 Da        Isoelectric Point: 7.4648

>NTDB_id=1111442 ACN076_RS03115 WP_050283620.1 626488..627177(+) (covR) [Streptococcus sp. K0074]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1111442 ACN076_RS03115 WP_050283620.1 626488..627177(+) (covR) [Streptococcus sp. K0074]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAGCTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCTATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCATCTGGGGGATATGACAGCCCAGGATTTTGCAGACAAGCTGAGTCGGACTAAGCCAGCCTCAGTCATCATGGTCTTG
GACCATCGTGAAGAATTGCAAGATCAGATTGAAACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCGGTTATTAT
TGACAATTTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACATCTTACCGCAATCTACGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAAATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCTACTCTTATGGGGAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACAAATATCGTGGATGTCTACATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTCGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9GD25

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment