Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   DP15_RS07075 Genome accession   NZ_CP008926
Coordinates   1391996..1392952 (+) Length   318 a.a.
NCBI ID   WP_046166194.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain ATCC 19615     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1386996..1397952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP15_RS07045 (DP15_1444) - 1387128..1387355 (+) 228 WP_028797129.1 Blp family class II bacteriocin -
  DP15_RS07050 (DP15_1445) - 1387404..1387721 (+) 318 WP_002994587.1 hypothetical protein -
  DP15_RS10125 - 1387841..1388926 (+) 1086 Protein_1348 IS3 family transposase -
  DP15_RS07065 - 1389140..1390634 (+) 1495 Protein_1349 IS1182 family transposase -
  DP15_RS07070 (DP15_1449) comE/blpR 1390869..1391618 (+) 750 WP_002992578.1 response regulator transcription factor Regulator
  DP15_RS07075 (DP15_1450) comD/blpH 1391996..1392952 (+) 957 WP_046166194.1 sensor histidine kinase Regulator
  DP15_RS09650 (DP15_1451) - 1393100..1393225 (-) 126 WP_011017462.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DP15_RS07080 (DP15_1452) - 1393302..1394666 (-) 1365 WP_014635340.1 bacteriocin secretion accessory protein -
  DP15_RS07085 (DP15_1453) comA/nlmT 1394677..1396830 (-) 2154 WP_038432843.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 36680.03 Da        Isoelectric Point: 8.2412

>NTDB_id=110988 DP15_RS07075 WP_046166194.1 1391996..1392952(+) (comD/blpH) [Streptococcus pyogenes strain ATCC 19615]
MIFSIVAGTMVLLLIQAFNYDFSHLRKKKLNQRTRTIISIANFSMILYFITIPMIDFIEEVENINFTHYQEMITAIYFLL
FICFVNLLDRNLRQELQKQVVLQKELQLQNMARYSKQIEGLYQNIRSFRHDYANILTSLKIGIDCKDIEMISSIYHKVLK
DSGKVLRGEKFNLARLRNINDLPLKSLLFVKLSEAQRLSIPVSIEIGEPISIKNIELIDFLTLVSILIDNAIEGAAESGI
VLCFFEQFGKQILIVQNDTFEKQINLSTIFERGVSSKGNNRGVGLSNVREILESYPTVTLKTVSNHFVFKQILEIEIL

Nucleotide


Download         Length: 957 bp        

>NTDB_id=110988 DP15_RS07075 WP_046166194.1 1391996..1392952(+) (comD/blpH) [Streptococcus pyogenes strain ATCC 19615]
ATGATTTTTTCTATTGTTGCTGGTACTATGGTTTTGCTGCTGATTCAAGCTTTTAATTATGACTTTAGTCATTTAAGAAA
AAAGAAACTAAATCAACGTACTAGAACGATTATATCTATTGCCAACTTTAGCATGATATTGTACTTTATTACCATTCCAA
TGATAGATTTTATCGAAGAAGTTGAAAATATTAATTTTACGCACTATCAAGAGATGATAACAGCAATTTATTTTCTTTTA
TTTATTTGTTTTGTAAATTTATTGGATCGGAACTTACGCCAAGAATTACAAAAGCAAGTTGTTCTACAAAAAGAGTTACA
ATTACAGAATATGGCTCGCTATAGTAAGCAAATCGAAGGACTGTATCAAAATATCAGAAGTTTTAGACATGATTATGCAA
ATATTTTAACAAGCTTGAAAATAGGCATTGATTGCAAAGATATTGAAATGATTTCAAGCATTTATCATAAGGTGTTGAAA
GATTCAGGGAAGGTTTTAAGGGGAGAAAAATTCAATCTAGCAAGGCTGAGAAATATAAACGACCTCCCTCTGAAAAGTTT
ACTGTTTGTAAAATTATCAGAAGCTCAACGCTTATCCATACCTGTATCTATAGAAATTGGGGAACCGATTTCTATAAAAA
ACATTGAGTTAATCGATTTTTTAACCCTTGTTTCTATCTTGATAGATAATGCAATCGAAGGTGCAGCAGAGTCGGGGATA
GTTCTTTGTTTTTTTGAACAATTTGGTAAACAGATATTAATTGTTCAAAATGATACTTTTGAAAAACAGATTAATCTTTC
CACGATTTTTGAGCGAGGTGTTTCTTCAAAAGGAAATAATAGGGGAGTTGGTTTATCAAATGTCAGGGAGATATTAGAAT
CATATCCCACTGTTACCCTCAAAACAGTAAGTAATCATTTTGTTTTTAAACAGATTCTAGAAATAGAAATCCTATAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(216-313)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

40.391

96.541

0.39

Multiple sequence alignment