Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACOCI8_RS13040 Genome accession   NZ_CP184563
Coordinates   2644842..2645411 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus strain SCTW2018065     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2639842..2650411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACOCI8_RS13000 (ACOCI8_13000) - 2640316..2640924 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  ACOCI8_RS13005 (ACOCI8_13005) rplL 2641099..2641467 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACOCI8_RS13010 (ACOCI8_13010) rplJ 2641510..2642010 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACOCI8_RS13015 (ACOCI8_13015) rplA 2642282..2642974 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACOCI8_RS13020 (ACOCI8_13020) rplK 2643182..2643604 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACOCI8_RS13025 (ACOCI8_13025) nusG 2643785..2644333 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACOCI8_RS13030 (ACOCI8_13030) secE 2644346..2644528 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACOCI8_RS13035 (ACOCI8_13035) rpmG 2644584..2644727 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACOCI8_RS13040 (ACOCI8_13040) sigH 2644842..2645411 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACOCI8_RS13045 (ACOCI8_13045) - 2645493..2646017 (-) 525 WP_000664738.1 NYN domain-containing protein -
  ACOCI8_RS13050 (ACOCI8_13050) rlmB 2646017..2646763 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACOCI8_RS13055 (ACOCI8_13055) - 2646771..2647175 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  ACOCI8_RS13060 (ACOCI8_13060) cysS 2647168..2648568 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  ACOCI8_RS13065 (ACOCI8_13065) cysE 2648552..2649199 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1109605 ACOCI8_RS13040 WP_000872879.1 2644842..2645411(-) (sigH) [Staphylococcus aureus strain SCTW2018065]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1109605 ACOCI8_RS13040 WP_000872879.1 2644842..2645411(-) (sigH) [Staphylococcus aureus strain SCTW2018065]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment