Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   DP15_RS04625 Genome accession   NZ_CP008926
Coordinates   926639..927406 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain ATCC 19615     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 921639..932406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP15_RS04615 (DP15_951) hexB 922170..924152 (-) 1983 WP_002992189.1 DNA mismatch repair endonuclease MutL Machinery gene
  DP15_RS04620 (DP15_952) - 924247..925398 (-) 1152 WP_003058754.1 site-specific integrase -
  DP15_RS10085 - 925737..925790 (+) 54 WP_229020936.1 hypothetical protein -
  DP15_RS04625 (DP15_953) irvR 926639..927406 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  DP15_RS04630 (DP15_954) - 927560..927766 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  DP15_RS04635 (DP15_955) - 927851..928000 (+) 150 WP_021340702.1 helix-turn-helix domain-containing protein -
  DP15_RS04640 (DP15_956) - 928021..928428 (+) 408 WP_002992501.1 hypothetical protein -
  DP15_RS10190 (DP15_957) - 928441..928563 (+) 123 WP_011285272.1 hypothetical protein -
  DP15_RS04645 (DP15_958) - 928846..929367 (+) 522 WP_002992498.1 Rha family transcriptional regulator -
  DP15_RS04650 (DP15_959) - 929612..929944 (+) 333 WP_002992497.1 hypothetical protein -
  DP15_RS04655 (DP15_960) - 929944..930135 (+) 192 WP_027968868.1 hypothetical protein -
  DP15_RS04660 (DP15_961) - 930148..930510 (+) 363 WP_000206026.1 hypothetical protein -
  DP15_RS04665 (DP15_962) - 930507..930836 (+) 330 WP_000174505.1 hypothetical protein -
  DP15_RS04670 (DP15_963) - 930839..931111 (+) 273 WP_001100459.1 hypothetical protein -
  DP15_RS04675 (DP15_964) - 931112..931969 (+) 858 WP_011185073.1 primase alpha helix C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=110954 DP15_RS04625 WP_003058809.1 926639..927406(-) (irvR) [Streptococcus pyogenes strain ATCC 19615]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=110954 DP15_RS04625 WP_003058809.1 926639..927406(-) (irvR) [Streptococcus pyogenes strain ATCC 19615]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4

Multiple sequence alignment