Detailed information NTG1109494

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: ACOCJH_RS07980
• Genome accession: NZ_CP184559
• Coordinates: 1636071..1636568 (-)
• Length: 165 a.a.
• NCBI ID: WP_001825340.1
• Uniprot ID: A0A2S6DDC2
• Organism: Staphylococcus aureus strain CBTW2018367
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1631071..1641568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJH_RS07955 (ACOCJH_07955)	gcvPB	1631233..1632705 (-)	1473	WP_000202179.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	-
ACOCJH_RS07960 (ACOCJH_07960)	gcvPA	1632698..1634044 (-)	1347	WP_000019698.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
ACOCJH_RS07965 (ACOCJH_07965)	gcvT	1634064..1635155 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
ACOCJH_RS07970 (ACOCJH_07970)	-	1635314..1635838 (-)	525	WP_001015120.1	shikimate kinase	-
ACOCJH_RS07975 (ACOCJH_07975)	-	1635828..1635974 (-)	147	WP_001789879.1	hypothetical protein	-
ACOCJH_RS07980 (ACOCJH_07980)	comGF	1636071..1636568 (-)	498	WP_001825340.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACOCJH_RS07985 (ACOCJH_07985)	comGE	1636486..1636785 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
ACOCJH_RS07990 (ACOCJH_07990)	comGD	1636772..1637218 (-)	447	WP_001796473.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACOCJH_RS07995 (ACOCJH_07995)	comGC	1637196..1637507 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
ACOCJH_RS08000 (ACOCJH_08000)	comGB	1637521..1638591 (-)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACOCJH_RS08005 (ACOCJH_08005)	comGA	1638563..1639537 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACOCJH_RS08010 (ACOCJH_08010)	-	1639589..1640212 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACOCJH_RS08015 (ACOCJH_08015)	-	1640209..1640538 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACOCJH_RS08020 (ACOCJH_08020)	-	1640538..1641524 (-)	987	WP_000161315.1	ROK family glucokinase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 19179.92 Da
• Isoelectric Point: 10.2192

>NTDB_id=1109494 ACOCJH_RS07980 WP_001825340.1 1636071..1636568(-) (comGF) [Staphylococcus aureus strain CBTW2018367]
MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDI
LEDFKGVDRNDIEIRQQRIILHKGEEMIEYKLINNKIIKVVNDRGNITLINNVTAFTANIYYKSIIKITITVKVGTNLQT
KTIYV

Nucleotide

• Length: 498 bp

>NTDB_id=1109494 ACOCJH_RS07980 WP_001825340.1 1636071..1636568(-) (comGF) [Staphylococcus aureus strain CBTW2018367]
ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCGCTTATTGAAATGTTAGTAGCGATGATGGTTATAAGCATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAGCAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGAGGATTTTAAAGGTGTAGATAGAAACGATATTGAAATTAGGCAACAGCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACATTGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCTATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATCTGCAGACT
AAAACTATTTATGTATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (28-51)

• Putative Competence protein ComGF (ComGF) (68-155)

3D structure

• AlphaFold DB: A0A2S6DDC2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Staphylococcus aureus N315	98.182	100	0.982
comGF	Staphylococcus aureus MW2	96.97	100	0.97