Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACOCJK_RS02625 Genome accession   NZ_CP184541
Coordinates   558874..559443 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus strain SCTW2022336     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 553874..564443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACOCJK_RS02600 (ACOCJK_02600) cysE 555086..555733 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  ACOCJK_RS02605 (ACOCJK_02605) cysS 555717..557117 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  ACOCJK_RS02610 (ACOCJK_02610) - 557110..557514 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  ACOCJK_RS02615 (ACOCJK_02615) rlmB 557522..558268 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACOCJK_RS02620 (ACOCJK_02620) - 558268..558792 (+) 525 WP_000664738.1 NYN domain-containing protein -
  ACOCJK_RS02625 (ACOCJK_02625) sigH 558874..559443 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACOCJK_RS02630 (ACOCJK_02630) rpmG 559558..559701 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACOCJK_RS02635 (ACOCJK_02635) secE 559757..559939 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACOCJK_RS02640 (ACOCJK_02640) nusG 559952..560500 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACOCJK_RS02645 (ACOCJK_02645) rplK 560681..561103 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACOCJK_RS02650 (ACOCJK_02650) rplA 561311..562003 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACOCJK_RS02655 (ACOCJK_02655) rplJ 562275..562775 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACOCJK_RS02660 (ACOCJK_02660) rplL 562818..563186 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACOCJK_RS02665 (ACOCJK_02665) - 563361..563969 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1109126 ACOCJK_RS02625 WP_000872879.1 558874..559443(+) (sigH) [Staphylococcus aureus strain SCTW2022336]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1109126 ACOCJK_RS02625 WP_000872879.1 558874..559443(+) (sigH) [Staphylococcus aureus strain SCTW2022336]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment