Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ID09_RS00275 Genome accession   NZ_CP008921
Coordinates   45253..47190 (+) Length   645 a.a.
NCBI ID   WP_024381980.1    Uniprot ID   -
Organism   Streptococcus suis 6407     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 40253..52190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS00255 (ID09_00280) - 41135..42073 (-) 939 WP_024381983.1 IS4 family transposase -
  ID09_RS00260 (ID09_00285) - 42210..43430 (+) 1221 WP_024381982.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  ID09_RS00270 (ID09_00290) - 43621..45144 (+) 1524 WP_024390804.1 quinol oxidase -
  ID09_RS00275 (ID09_00295) hexB 45253..47190 (+) 1938 WP_024381980.1 DNA mismatch repair endonuclease MutL Machinery gene
  ID09_RS00280 (ID09_00300) ruvA 47229..47819 (+) 591 WP_011921679.1 Holliday junction branch migration protein RuvA Machinery gene
  ID09_RS00285 (ID09_00305) - 47978..48538 (+) 561 WP_024381979.1 DNA-3-methyladenine glycosylase I -
  ID09_RS00290 (ID09_00310) - 48612..49022 (+) 411 WP_024381978.1 helix-turn-helix transcriptional regulator -
  ID09_RS11320 (ID09_00315) - 48995..49660 (+) 666 WP_024381977.1 CPBP family intramembrane glutamic endopeptidase -
  ID09_RS00300 (ID09_00320) cinA 49805..50986 (+) 1182 WP_024381976.1 competence/damage-inducible protein A Machinery gene
  ID09_RS00305 (ID09_00325) recA 51038..52189 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72922.12 Da        Isoelectric Point: 5.1710

>NTDB_id=110811 ID09_RS00275 WP_024381980.1 45253..47190(+) (hexB) [Streptococcus suis 6407]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALNLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=110811 ID09_RS00275 WP_024381980.1 45253..47190(+) (hexB) [Streptococcus suis 6407]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCTATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCCTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGCCTAGCTCATCCGGAAATAGCCTT
TGCCTTAGTAAACGAAGGAAGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCCGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTACGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTTAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGATGTTGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCCTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTAACCTTGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTGGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAAGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCCATCATGATGTCTTGTAAACGGTCAATCAAGGCCAATCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAATTGCCCGCACGGCC
GCCCAGTCTTAGTGCATTTTAGCAAGTCAGATATGGAAAAGATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(447-589)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.615

100

0.732

Multiple sequence alignment