Detailed information NTG1106120

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM595_RS04830
• Genome accession: NZ_CP183796
• Coordinates: 972701..973744 (-)
• Length: 347 a.a.
• NCBI ID: WP_419744454.1
• Uniprot ID: -
• Organism: Staphylococcus sp. LKG3-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 967701..978744

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM595_RS04800 (ACM595_04800)	-	967996..969234 (-)	1239	WP_115338454.1	aminopeptidase	-
ACM595_RS04805 (ACM595_04805)	-	969248..969451 (-)	204	WP_002482850.1	DUF1128 family protein	-
ACM595_RS04810 (ACM595_04810)	-	969586..970050 (+)	465	WP_011302783.1	low molecular weight protein-tyrosine-phosphatase	-
ACM595_RS04815 (ACM595_04815)	-	970057..970341 (+)	285	WP_002482848.1	hypothetical protein	-
ACM595_RS04820 (ACM595_04820)	-	970753..971931 (+)	1179	WP_419744453.1	YihY/virulence factor BrkB family protein	-
ACM595_RS04825 (ACM595_04825)	vraR	972082..972711 (-)	630	WP_002482846.1	response regulator transcription factor	Regulator
ACM595_RS04830 (ACM595_04830)	vraS	972701..973744 (-)	1044	WP_419744454.1	sensor histidine kinase	Regulator
ACM595_RS04835 (ACM595_04835)	liaF	973741..974442 (-)	702	WP_011302780.1	cell wall-active antibiotics response protein LiaF	-
ACM595_RS04840 (ACM595_04840)	-	974459..974845 (-)	387	WP_041079966.1	hypothetical protein	-
ACM595_RS04845 (ACM595_04845)	map	974949..975701 (-)	753	WP_011302778.1	type I methionyl aminopeptidase	-
ACM595_RS04850 (ACM595_04850)	-	975876..976862 (+)	987	WP_002482841.1	FUSC family protein	-
ACM595_RS04855 (ACM595_04855)	-	977001..977720 (-)	720	WP_115338453.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40050.59 Da
• Isoelectric Point: 6.5963

>NTDB_id=1106120 ACM595_RS04830 WP_419744454.1 972701..973744(-) (vraS) [Staphylococcus sp. LKG3-1]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDKNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=1106120 ACM595_RS04830 WP_419744454.1 972701..973744(-) (vraS) [Staphylococcus sp. LKG3-1]
ATGAATCACTACTTTAGAGCGATCGGGTCCATGTTGATATTAGTATATAGTACGTTTTTTGCCATATTCTTTATTGATAA
AGTGTTTGTTAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCTGTACTGCTTTTTTTAAATC
TAATGGTGATTTTACTCTGTATTATTGTAGGTTCTGTCTTAGCATATAAAATCAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAACGTTCAATAGAAGGTCAAACAGTGGGTATCAATGATAAAAATATTGAATTATACAACGAAACAATCGAACT
ATATCAAACGCTTGTGCCGTTAAATCAAGAAGTACATAAATTAAGAATGAAAACACAGAACCTGACGAATGAATCTTATA
ATATCAATGATGTTAAAGTTAAGAAAATTATAGAAGACGAACGTCAACGTTTAGCGCGTGAATTACATGATTCAGTTAGT
CAACAATTATTCGCAGCAAGTATGATGTTATCAGCAATTAAAGAGACAGAATTGAAGGCCCCATTGGACCAACAAATACC
AGTATTAGAAAAAATGATTCAAGATTCCCAATTAGAAATGAGAGCACTACTATTACACTTAAGACCTATTGGTTTGAAAG
ATAAATCTTTAGGTGAGGGTATTAAAGATTTAGTCGTTGATTTACAGAAAAAAGTACCAATGAAAGTGGTACATGATATT
GAAGAATTCAAAGTACCAAAAGGTATCGAGGACCATTTATTCCGTATTACGCAAGAAGCCATTTCTAATACGCTAAGACA
TTCTAAAGGAACGAAGGTCACAATTGAATTATTTAATAGGGAAGAATATTTGTTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGCGAACGTGCACTAGAAATAGGTGCAACA
TTTCATATCGTTTCTTTGCCTGATGCAGGTACGAGAATTGAAGTGAAGGCACCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.032	100	0.87