Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACM595_RS04825 Genome accession   NZ_CP183796
Coordinates   972082..972711 (-) Length   209 a.a.
NCBI ID   WP_002482846.1    Uniprot ID   A0A380HJV9
Organism   Staphylococcus sp. LKG3-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 967082..977711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM595_RS04795 (ACM595_04795) - 967261..967782 (-) 522 WP_037538134.1 acyl-CoA thioesterase -
  ACM595_RS04800 (ACM595_04800) - 967996..969234 (-) 1239 WP_115338454.1 aminopeptidase -
  ACM595_RS04805 (ACM595_04805) - 969248..969451 (-) 204 WP_002482850.1 DUF1128 family protein -
  ACM595_RS04810 (ACM595_04810) - 969586..970050 (+) 465 WP_011302783.1 low molecular weight protein-tyrosine-phosphatase -
  ACM595_RS04815 (ACM595_04815) - 970057..970341 (+) 285 WP_002482848.1 hypothetical protein -
  ACM595_RS04820 (ACM595_04820) - 970753..971931 (+) 1179 WP_419744453.1 YihY/virulence factor BrkB family protein -
  ACM595_RS04825 (ACM595_04825) vraR 972082..972711 (-) 630 WP_002482846.1 response regulator transcription factor Regulator
  ACM595_RS04830 (ACM595_04830) vraS 972701..973744 (-) 1044 WP_419744454.1 sensor histidine kinase Regulator
  ACM595_RS04835 (ACM595_04835) liaF 973741..974442 (-) 702 WP_011302780.1 cell wall-active antibiotics response protein LiaF -
  ACM595_RS04840 (ACM595_04840) - 974459..974845 (-) 387 WP_041079966.1 hypothetical protein -
  ACM595_RS04845 (ACM595_04845) map 974949..975701 (-) 753 WP_011302778.1 type I methionyl aminopeptidase -
  ACM595_RS04850 (ACM595_04850) - 975876..976862 (+) 987 WP_002482841.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23684.19 Da        Isoelectric Point: 4.6997

>NTDB_id=1106119 ACM595_RS04825 WP_002482846.1 972082..972711(-) (vraR) [Staphylococcus sp. LKG3-1]
MPIKVLFVDDHEMVRIGISSYLSTQSDIDVVGEGKSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQVKKDLPNIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1106119 ACM595_RS04825 WP_002482846.1 972082..972711(-) (vraR) [Staphylococcus sp. LKG3-1]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAAATGGTTCGAATAGGTATTTCTAGTTATTTATCCACACAATCTGA
TATAGATGTCGTAGGGGAAGGTAAGTCAGGAAAAGATGCAATCGAAAAAGCACATGAACTGAAACCGGACCTAATTTTAA
TGGATTTACTTATGGACGATATGGATGGTGTCGAAGCAACTGAACAAGTTAAAAAAGACTTGCCAAATATTAAAGTTGTC
ATGCTTACGAGTTATATTGAAGATAACGAAGTCTATCGTGCACTTGATTCCGGTGTAGATAGCTATATATTGAAAACAAC
AAGTGCTAGTGATATTGCTGAAGCGATTCGTAAGACTTACAATAATGAGTCAGTATTTGAAGCAGAAGTCCTAGTTAAAA
TGAGAAATAGGATGAAACAACGAGCTGAATTGTATGAAATGCTCACAGAACGTGAAATGGAGATTTTATTACTGATTGCT
AAAGGTTACTCTAACCAAGAGATTGCCAGCGCTTCACATATTACGATTAAAACAGTGAAAACGCATGTAAGTAATATCCT
AAGTAAATTAGAAGTTCAAGATAGAACTCAAGCCGTCATATATGCATTCCAGCACAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380HJV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.952

100

0.9

Multiple sequence alignment