Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | ACM595_RS00340 | Genome accession | NZ_CP183796 |
| Coordinates | 81220..81786 (+) | Length | 188 a.a. |
| NCBI ID | WP_041079011.1 | Uniprot ID | A0A380HNJ5 |
| Organism | Staphylococcus sp. LKG3-1 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 82277..124570 | 81220..81786 | flank | 491 |
Gene organization within MGE regions
Location: 81220..124570
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACM595_RS00340 (ACM595_00340) | comK/comK1 | 81220..81786 (+) | 567 | WP_041079011.1 | competence protein ComK | Regulator |
| ACM595_RS00355 (ACM595_00355) | - | 82277..83332 (-) | 1056 | WP_419744367.1 | tyrosine-type recombinase/integrase | - |
| ACM595_RS00360 (ACM595_00360) | - | 83392..84030 (-) | 639 | WP_419744368.1 | hypothetical protein | - |
| ACM595_RS00365 (ACM595_00365) | - | 84045..84509 (-) | 465 | WP_419744369.1 | ImmA/IrrE family metallo-endopeptidase | - |
| ACM595_RS00370 (ACM595_00370) | - | 84521..84835 (-) | 315 | WP_210136405.1 | helix-turn-helix domain-containing protein | - |
| ACM595_RS00375 (ACM595_00375) | - | 84988..85200 (+) | 213 | WP_210136404.1 | helix-turn-helix transcriptional regulator | - |
| ACM595_RS00380 (ACM595_00380) | - | 85242..86204 (+) | 963 | WP_419744370.1 | hypothetical protein | - |
| ACM595_RS00385 (ACM595_00385) | - | 86197..86736 (+) | 540 | WP_419744371.1 | ORF6C domain-containing protein | - |
| ACM595_RS00390 (ACM595_00390) | - | 86782..87108 (+) | 327 | WP_210136401.1 | DUF771 domain-containing protein | - |
| ACM595_RS00395 (ACM595_00395) | - | 87121..87294 (+) | 174 | WP_419744372.1 | hypothetical protein | - |
| ACM595_RS00400 (ACM595_00400) | - | 87356..87580 (+) | 225 | WP_326024551.1 | DUF2483 family protein | - |
| ACM595_RS00405 (ACM595_00405) | - | 87573..88205 (+) | 633 | WP_419744373.1 | DUF1071 domain-containing protein | - |
| ACM595_RS00410 (ACM595_00410) | ssbA | 88195..88635 (+) | 441 | WP_419744374.1 | single-stranded DNA-binding protein | Machinery gene |
| ACM595_RS00415 (ACM595_00415) | - | 88649..89320 (+) | 672 | WP_419744375.1 | putative HNHc nuclease | - |
| ACM595_RS00420 (ACM595_00420) | - | 89317..90069 (+) | 753 | WP_419744376.1 | DnaD domain protein | - |
| ACM595_RS00425 (ACM595_00425) | - | 90073..90435 (+) | 363 | WP_419744377.1 | hypothetical protein | - |
| ACM595_RS00430 (ACM595_00430) | - | 90431..91666 (+) | 1236 | WP_419744484.1 | DnaB helicase C-terminal domain-containing protein | - |
| ACM595_RS00435 (ACM595_00435) | - | 91663..91875 (+) | 213 | WP_419744378.1 | hypothetical protein | - |
| ACM595_RS00440 (ACM595_00440) | - | 91862..92098 (+) | 237 | WP_129303566.1 | DUF3269 family protein | - |
| ACM595_RS00445 (ACM595_00445) | - | 92109..92510 (+) | 402 | WP_069822265.1 | DUF1064 domain-containing protein | - |
| ACM595_RS00450 (ACM595_00450) | - | 92507..92719 (+) | 213 | WP_419744379.1 | hypothetical protein | - |
| ACM595_RS00455 (ACM595_00455) | - | 92733..93086 (+) | 354 | WP_419744380.1 | SA1788 family PVL leukocidin-associated protein | - |
| ACM595_RS00460 (ACM595_00460) | - | 93603..93818 (+) | 216 | Protein_89 | DUF3310 domain-containing protein | - |
| ACM595_RS00465 (ACM595_00465) | - | 93819..94124 (+) | 306 | WP_419744381.1 | DUF1140 family protein | - |
| ACM595_RS00470 (ACM595_00470) | - | 94187..94333 (+) | 147 | WP_419744382.1 | hypothetical protein | - |
| ACM595_RS00475 (ACM595_00475) | - | 94326..94679 (+) | 354 | WP_419744383.1 | hypothetical protein | - |
| ACM595_RS00480 (ACM595_00480) | - | 94682..94951 (+) | 270 | WP_210146124.1 | hypothetical protein | - |
| ACM595_RS00485 (ACM595_00485) | - | 95147..95506 (+) | 360 | WP_419744485.1 | MazG-like family protein | - |
| ACM595_RS00490 (ACM595_00490) | - | 95592..95834 (+) | 243 | WP_419744384.1 | hypothetical protein | - |
| ACM595_RS00495 (ACM595_00495) | - | 95834..96067 (+) | 234 | WP_419744385.1 | DUF1381 domain-containing protein | - |
| ACM595_RS00500 (ACM595_00500) | rinB | 96064..96210 (+) | 147 | WP_419744386.1 | transcriptional activator RinB | - |
| ACM595_RS00505 (ACM595_00505) | - | 96226..96642 (+) | 417 | WP_419744387.1 | transcriptional regulator | - |
| ACM595_RS00510 (ACM595_00510) | - | 96874..97542 (+) | 669 | WP_419744388.1 | hypothetical protein | - |
| ACM595_RS00515 (ACM595_00515) | - | 97605..98042 (+) | 438 | WP_419744389.1 | terminase small subunit | - |
| ACM595_RS00520 (ACM595_00520) | - | 98051..99319 (+) | 1269 | WP_419744390.1 | PBSX family phage terminase large subunit | - |
| ACM595_RS00525 (ACM595_00525) | - | 99324..100757 (+) | 1434 | WP_419744391.1 | phage portal protein | - |
| ACM595_RS00530 (ACM595_00530) | - | 100771..101670 (+) | 900 | WP_419744392.1 | phage minor head protein | - |
| ACM595_RS00535 (ACM595_00535) | - | 101764..102357 (+) | 594 | WP_419744393.1 | phage scaffolding protein | - |
| ACM595_RS00540 (ACM595_00540) | - | 102376..103194 (+) | 819 | WP_419744394.1 | N4-gp56 family major capsid protein | - |
| ACM595_RS00545 (ACM595_00545) | - | 103209..103502 (+) | 294 | WP_419744395.1 | Rho termination factor N-terminal domain-containing protein | - |
| ACM595_RS00550 (ACM595_00550) | - | 103502..103816 (+) | 315 | WP_419744396.1 | phage head-tail connector protein | - |
| ACM595_RS00555 (ACM595_00555) | - | 103809..104141 (+) | 333 | WP_419744397.1 | phage head closure protein | - |
| ACM595_RS00560 (ACM595_00560) | - | 104134..104550 (+) | 417 | WP_419744398.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| ACM595_RS00565 (ACM595_00565) | - | 104563..104985 (+) | 423 | WP_419744399.1 | DUF3168 domain-containing protein | - |
| ACM595_RS00570 (ACM595_00570) | - | 104989..105516 (+) | 528 | WP_078072853.1 | phage tail protein | - |
| ACM595_RS00575 (ACM595_00575) | - | 105575..106072 (+) | 498 | WP_419744400.1 | tail assembly chaperone | - |
| ACM595_RS00580 (ACM595_00580) | - | 106126..106422 (+) | 297 | WP_419744401.1 | hypothetical protein | - |
| ACM595_RS00585 (ACM595_00585) | - | 106426..109362 (+) | 2937 | WP_419744402.1 | phage tail protein | - |
| ACM595_RS00590 (ACM595_00590) | - | 109374..110288 (+) | 915 | WP_419744403.1 | phage tail protein | - |
| ACM595_RS00595 (ACM595_00595) | - | 110303..111775 (+) | 1473 | WP_419744404.1 | DUF7643 domain-containing protein | - |
| ACM595_RS00600 (ACM595_00600) | - | 111775..113664 (+) | 1890 | WP_419744405.1 | hypothetical protein | - |
| ACM595_RS00605 (ACM595_00605) | - | 113665..115590 (+) | 1926 | WP_419744406.1 | BppU family phage baseplate upper protein | - |
| ACM595_RS00610 (ACM595_00610) | - | 115590..115937 (+) | 348 | WP_419744407.1 | DUF2977 domain-containing protein | - |
| ACM595_RS00615 (ACM595_00615) | - | 115924..116085 (+) | 162 | WP_078072845.1 | XkdX family protein | - |
| ACM595_RS00620 (ACM595_00620) | - | 116123..116557 (+) | 435 | WP_419744408.1 | hypothetical protein | - |
| ACM595_RS00625 (ACM595_00625) | - | 116541..116945 (+) | 405 | WP_078072843.1 | hypothetical protein | - |
| ACM595_RS00630 (ACM595_00630) | - | 116998..118923 (+) | 1926 | WP_419744409.1 | glucosaminidase domain-containing protein | - |
| ACM595_RS00635 (ACM595_00635) | - | 119065..121296 (+) | 2232 | WP_419744410.1 | BppU family phage baseplate upper protein | - |
| ACM595_RS00640 (ACM595_00640) | - | 121379..121666 (+) | 288 | WP_419744411.1 | phage holin | - |
| ACM595_RS00645 (ACM595_00645) | - | 121677..123056 (+) | 1380 | WP_419744412.1 | N-acetylmuramoyl-L-alanine amidase | - |
| ACM595_RS00650 (ACM595_00650) | - | 123367..123678 (+) | 312 | WP_174605002.1 | DUF3467 domain-containing protein | - |
| ACM595_RS00655 (ACM595_00655) | - | 123665..124060 (+) | 396 | WP_239466229.1 | hypothetical protein | - |
| ACM595_RS00660 (ACM595_00660) | - | 124160..124570 (+) | 411 | WP_419744413.1 | YolD-like family protein | - |
Sequence
Protein
Download Length: 188 a.a. Molecular weight: 22118.54 Da Isoelectric Point: 9.5133
>NTDB_id=1106102 ACM595_RS00340 WP_041079011.1 81220..81786(+) (comK/comK1) [Staphylococcus sp. LKG3-1]
MIQPYIIKKGDMVLQPCSLSTGKYEGSYLLKYKDDSKVLKERVPKIIDRSCRFYGSSYHFKKEDTMRITGISSKPPILFT
PLFPTYFFPTHSDRKEENTWINIHYVHQIKPLKEKKCKVTFVDNQTIVANISAHSMHHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFENKS
MIQPYIIKKGDMVLQPCSLSTGKYEGSYLLKYKDDSKVLKERVPKIIDRSCRFYGSSYHFKKEDTMRITGISSKPPILFT
PLFPTYFFPTHSDRKEENTWINIHYVHQIKPLKEKKCKVTFVDNQTIVANISAHSMHHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFENKS
Nucleotide
Download Length: 567 bp
>NTDB_id=1106102 ACM595_RS00340 WP_041079011.1 81220..81786(+) (comK/comK1) [Staphylococcus sp. LKG3-1]
ATGATTCAACCCTATATCATTAAAAAAGGGGATATGGTTTTACAACCATGCAGTTTATCAACTGGTAAGTATGAAGGTAG
TTATCTTTTAAAGTATAAGGATGACAGCAAAGTTCTAAAAGAACGTGTTCCAAAGATTATTGATCGATCGTGTAGATTTT
ATGGTAGTAGTTATCATTTTAAGAAAGAAGATACGATGAGAATTACTGGCATAAGCAGTAAACCCCCAATTTTATTTACT
CCACTTTTTCCTACTTATTTTTTCCCAACGCACTCTGATAGAAAAGAAGAAAATACTTGGATTAATATTCATTATGTTCA
CCAAATCAAACCACTAAAAGAAAAGAAATGTAAAGTGACATTTGTAGATAATCAAACAATTGTAGCTAACATTTCAGCAC
ATAGCATGCATCATCAATACCTAAATGGTATTTATTATTACTATATGATGGATAGGGCAGCAAGAGTTGCTACCTTTGAT
CCAGAATCTCCTATTGATTATACAAAACCTCAATTAAATATTTATGAAGCATTAGCAAAATATTCATTATTTGAAAATAA
ATCGTAG
ATGATTCAACCCTATATCATTAAAAAAGGGGATATGGTTTTACAACCATGCAGTTTATCAACTGGTAAGTATGAAGGTAG
TTATCTTTTAAAGTATAAGGATGACAGCAAAGTTCTAAAAGAACGTGTTCCAAAGATTATTGATCGATCGTGTAGATTTT
ATGGTAGTAGTTATCATTTTAAGAAAGAAGATACGATGAGAATTACTGGCATAAGCAGTAAACCCCCAATTTTATTTACT
CCACTTTTTCCTACTTATTTTTTCCCAACGCACTCTGATAGAAAAGAAGAAAATACTTGGATTAATATTCATTATGTTCA
CCAAATCAAACCACTAAAAGAAAAGAAATGTAAAGTGACATTTGTAGATAATCAAACAATTGTAGCTAACATTTCAGCAC
ATAGCATGCATCATCAATACCTAAATGGTATTTATTATTACTATATGATGGATAGGGCAGCAAGAGTTGCTACCTTTGAT
CCAGAATCTCCTATTGATTATACAAAACCTCAATTAAATATTTATGAAGCATTAGCAAAATATTCATTATTTGAAAATAA
ATCGTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
54.891 |
97.872 |
0.537 |
| comK/comK1 | Staphylococcus aureus N315 |
54.891 |
97.872 |
0.537 |