Detailed information NTG1105943

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: V3C22_RS04490
• Genome accession: NZ_CP183775
• Coordinates: 934127..935359 (+)
• Length: 410 a.a.
• NCBI ID: WP_002262816.1
• Uniprot ID: A0AAX1K4W9
• Organism: Streptococcus mutans strain Xc
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 929127..940359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V3C22_RS04465 (V3C22_04465)	-	930199..931374 (-)	1176	WP_002266471.1	hydroxymethylglutaryl-CoA synthase	-
V3C22_RS04470 (V3C22_04470)	-	931582..932421 (+)	840	WP_002264319.1	thymidylate synthase	-
V3C22_RS04475 (V3C22_04475)	pnuC	932538..933317 (+)	780	WP_002264318.1	nicotinamide riboside transporter PnuC	-
V3C22_RS04480 (V3C22_04480)	-	933402..933914 (+)	513	WP_226706801.1	dihydrofolate reductase	-
V3C22_RS04485 (V3C22_04485)	-	933932..934102 (+)	171	WP_002262815.1	hypothetical protein	-
V3C22_RS04490 (V3C22_04490)	clpX	934127..935359 (+)	1233	WP_002262816.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
V3C22_RS04495 (V3C22_04495)	yihA	935375..935968 (+)	594	WP_002262817.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
V3C22_RS04500 (V3C22_04500)	-	936298..937674 (+)	1377	WP_002303866.1	amino acid permease	-
V3C22_RS04505 (V3C22_04505)	mmuM	937684..938634 (+)	951	WP_226706803.1	homocysteine S-methyltransferase	-
V3C22_RS04510 (V3C22_04510)	-	938768..940030 (-)	1263	WP_002263804.1	PLP-dependent aminotransferase family protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45181.65 Da
• Isoelectric Point: 4.4495

>NTDB_id=1105943 V3C22_RS04490 WP_002262816.1 934127..935359(+) (clpX) [Streptococcus mutans strain Xc]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide

• Length: 1233 bp

>NTDB_id=1105943 V3C22_RS04490 WP_002262816.1 934127..935359(+) (clpX) [Streptococcus mutans strain Xc]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTGTTGGCAATACTAGACAGTTATGTTATCGGTCAGGATCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATT
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATCCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	100	100	1
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	97.805	0.578