Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   V3C22_RS02420 Genome accession   NZ_CP183775
Coordinates   496660..497961 (+) Length   433 a.a.
NCBI ID   WP_002270130.1    Uniprot ID   -
Organism   Streptococcus mutans strain Xc     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 491660..502961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3C22_RS02400 (V3C22_02400) - 492809..493477 (+) 669 WP_019314315.1 fructose-6-phosphate aldolase -
  V3C22_RS02405 (V3C22_02405) - 493516..494607 (+) 1092 WP_226707131.1 glycerol dehydrogenase -
  V3C22_RS02410 (V3C22_02410) cysK 494941..495867 (-) 927 WP_019315688.1 cysteine synthase A -
  V3C22_RS02415 (V3C22_02415) - 495958..496587 (-) 630 WP_002263027.1 YigZ family protein -
  V3C22_RS02420 (V3C22_02420) comFA/cflA 496660..497961 (+) 1302 WP_002270130.1 DEAD/DEAH box helicase Machinery gene
  V3C22_RS02425 (V3C22_02425) - 497958..498623 (+) 666 WP_002267952.1 ComF family protein -
  V3C22_RS02430 (V3C22_02430) hpf 498702..499250 (+) 549 WP_002263024.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  V3C22_RS02435 (V3C22_02435) - 499374..500468 (+) 1095 WP_226707127.1 hypothetical protein -
  V3C22_RS02440 (V3C22_02440) - 500488..502188 (+) 1701 WP_226707129.1 TcaA 3rd/4th domain-containing protein -
  V3C22_RS02445 (V3C22_02445) - 502268..502903 (-) 636 WP_002286443.1 hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49573.78 Da        Isoelectric Point: 10.0191

>NTDB_id=1105932 V3C22_RS02420 WP_002270130.1 496660..497961(+) (comFA/cflA) [Streptococcus mutans strain Xc]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNKLGNTLPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRDKLPRSFLQQIRIQRQTQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1105932 V3C22_RS02420 WP_002270130.1 496660..497961(+) (comFA/cflA) [Streptococcus mutans strain Xc]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGCCAGAACAAACTTGGTAATACTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGAGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGATAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACTTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAAATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

Type III restriction enzyme, res subunit (ResIII)

(94-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

58.782

98.614

0.58
  comFA/cflA Streptococcus mitis SK321

58.314

98.614

0.575
  comFA Lactococcus lactis subsp. cremoris KW2

51.777

90.993

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

38.732

98.383

0.381

Multiple sequence alignment