Detailed information NTG1105179

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: ACNVED_RS10115
• Genome accession: NZ_CP183303
• Coordinates: 2338851..2341589 (+)
• Length: 912 a.a.
• NCBI ID: WP_419418897.1
• Uniprot ID: -
• Organism: Legionella sp. D16C41
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2333851..2346589

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNVED_RS10100 (ACNVED_10100)	pmbA	2334672..2336030 (-)	1359	WP_419418894.1	metalloprotease PmbA	-
ACNVED_RS10105 (ACNVED_10105)	-	2336071..2336856 (+)	786	WP_419418895.1	phosphodiester glycosidase family protein	-
ACNVED_RS10110 (ACNVED_10110)	gltX	2337117..2338535 (-)	1419	WP_419418896.1	glutamate--tRNA ligase	-
ACNVED_RS10115 (ACNVED_10115)	letS	2338851..2341589 (+)	2739	WP_419418897.1	two-component system sensor histidine kinase LetS	Regulator
ACNVED_RS10120 (ACNVED_10120)	-	2341707..2342759 (+)	1053	WP_419418898.1	ankyrin repeat domain-containing protein	-
ACNVED_RS10125 (ACNVED_10125)	-	2343079..2344314 (+)	1236	WP_419418899.1	6-phosphofructokinase	-
ACNVED_RS10130 (ACNVED_10130)	pilA2	2344636..2345046 (-)	411	WP_419418900.1	pilin	Machinery gene
ACNVED_RS10135 (ACNVED_10135)	-	2345437..2345751 (+)	315	WP_419418901.1	BolA family protein	-
ACNVED_RS10140 (ACNVED_10140)	-	2345744..2346187 (+)	444	WP_419418902.1	secondary thiamine-phosphate synthase enzyme YjbQ	-

Sequence

Protein

• Length: 912 a.a.
• Molecular weight: 103456.97 Da
• Isoelectric Point: 7.0105

>NTDB_id=1105179 ACNVED_RS10115 WP_419418897.1 2338851..2341589(+) (letS) [Legionella sp. D16C41]
MKGLSIKYQLRLTTLIPVFVVALLFAVFYNGQFNKDLNQHMFRLGEAYIRQLLPAAQLAMMRNDRRTLQGLINASTINPE
VIALAFYDGDGHLMAYRGGKHSIHTPFKPPEFTGDYIESKQIEPYVINFVAPITIPKFNLYSNTTFKKTADYIPLQADDI
LGWLSIDIDTKSMLIKRYQMYIITIFITLFGLLISLTIHYLLSKRIYLPIARLRRSMKQILQNEFETHIAVSSDSELGEI
EKGCAHLQRQYLNTIHDLNHHIEVATEDLQNSLELLEEKNIQLSLEKKKTEEKIKQQSDFIANMTHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKSSSQDLLNIINDILDYSKMDAGKLHLDCIPLDLRACIDEVLTLAGPNAHKKGIDLIPSTGT
RVPKTVLGDPLRIKQILTNLISNAIKFTDHGYVLIRTLIEQESEKDYVVSIAITDTGIGISKDDQTKLFNAFNQADTSIT
RRFGGTGLGLVICKKLAEEMHGRIQLTSELHKGSTFTVKIRLEKLAAYEVEKNQTHRFGLLKAICFDDNPLQLEAMCNGI
GFWGIQCVAVNAFNQLEDAFKNHKECEIAFINVNEGCEKQVAQLLRKQTIPCVLVSKWLIHDPQALGARAFLYKPLSIQK
LYDTIEFILNEASQTVTNNHELDNLRKQLRAIHPEILIAEDNPVNRMLLSSLLQEHAAIELVENGEETLRACQEKRYNLL
LLDVQMPKLNGLEAAKLVRKESILNRRTPIVVISANTNDVKQEQLTKSGIDLCLEKPIDEKQLLTHLLRILNKTKALAID
WSLCVQKVSGNQILAEEFLTRFVEELTKSQPEFVTLFEQKDIKGLESAAHKLNGACCFCGVPRLQSQVIRLEKKAKEAKD
IAAIKEVFAEFMQSADEVIKEFENFYQAKSLN

Nucleotide

• Length: 2739 bp

>NTDB_id=1105179 ACNVED_RS10115 WP_419418897.1 2338851..2341589(+) (letS) [Legionella sp. D16C41]
ATGAAAGGCTTAAGTATTAAATATCAGCTTCGCCTGACGACATTAATCCCGGTTTTTGTAGTTGCCCTATTATTTGCTGT
TTTTTATAACGGTCAATTTAATAAAGACTTAAATCAGCATATGTTTCGTTTAGGAGAAGCTTATATCCGTCAATTATTAC
CTGCAGCCCAACTAGCTATGATGCGTAATGATAGACGAACGCTGCAAGGGCTTATTAACGCCTCAACTATTAATCCTGAG
GTTATCGCACTTGCCTTTTATGATGGTGATGGGCATTTAATGGCTTATCGAGGTGGAAAGCACTCTATTCATACACCATT
TAAACCTCCTGAATTTACCGGTGATTACATTGAAAGCAAACAAATTGAACCTTACGTAATTAATTTTGTCGCACCTATTA
CGATTCCTAAGTTTAACCTCTACTCAAATACCACTTTTAAAAAAACGGCAGACTATATACCACTGCAAGCGGATGATATT
TTAGGATGGCTATCCATTGACATTGATACCAAGTCAATGCTAATTAAACGTTATCAAATGTATATCATCACTATTTTTAT
TACTCTCTTTGGTTTATTAATTAGCCTTACCATTCACTACTTATTATCTAAACGCATTTACCTACCTATTGCCCGTTTAC
GGCGTAGTATGAAACAAATTTTACAAAATGAATTTGAAACACATATTGCTGTCTCTAGTGATAGCGAATTAGGAGAAATT
GAAAAAGGATGTGCGCACCTACAGCGTCAATATTTAAATACAATCCATGACCTTAATCATCATATTGAGGTTGCCACAGA
AGACTTACAAAATAGTCTTGAGCTTTTAGAAGAAAAAAATATTCAATTATCGCTAGAAAAGAAAAAGACTGAAGAAAAAA
TTAAACAGCAAAGCGATTTTATTGCCAACATGACTCATGAGATTCGAACTCCCATGAATGGTGTTATTGGTTTTACTAAT
GTTTTGTTAGAAAGCAAACTTGATCCCCTACAGCTAGATTATGTAAAAACGATTAAATCTTCTTCTCAAGATCTATTAAA
TATTATTAATGATATTTTAGATTACTCGAAAATGGATGCTGGCAAATTGCATCTTGATTGTATTCCACTTGATTTAAGAG
CCTGCATTGATGAAGTATTGACTTTAGCTGGTCCGAATGCTCATAAAAAAGGAATTGATTTAATTCCTTCTACAGGAACT
AGGGTTCCTAAAACTGTTTTAGGCGACCCATTACGTATAAAACAAATTTTGACCAATTTAATTAGTAATGCTATTAAGTT
TACCGATCATGGTTATGTTTTAATTCGCACCTTAATCGAACAAGAATCCGAAAAGGACTATGTAGTTTCTATTGCTATTA
CAGATACAGGTATCGGCATATCAAAAGACGACCAAACGAAGTTATTTAATGCTTTTAATCAAGCAGATACATCCATCACC
AGACGTTTTGGCGGTACTGGACTTGGGCTTGTGATTTGTAAAAAATTAGCAGAAGAAATGCATGGACGCATCCAATTAAC
CAGTGAGCTACATAAAGGGTCTACCTTTACAGTTAAAATTAGATTAGAGAAATTAGCAGCTTACGAAGTTGAAAAAAATC
AAACGCATCGATTCGGTCTATTAAAAGCTATTTGCTTTGACGATAATCCACTGCAACTTGAGGCCATGTGTAACGGGATA
GGCTTTTGGGGCATACAATGCGTTGCAGTTAATGCGTTTAACCAGTTAGAGGATGCCTTTAAAAACCATAAAGAATGCGA
GATTGCCTTTATTAATGTTAATGAAGGCTGCGAAAAGCAAGTTGCTCAATTATTACGGAAACAAACTATTCCTTGTGTTT
TAGTGTCCAAATGGCTTATTCATGACCCCCAAGCTTTAGGCGCGCGCGCCTTTTTATATAAACCATTAAGTATTCAAAAA
TTATACGATACGATTGAATTCATTCTTAATGAGGCGTCACAAACGGTAACTAATAATCATGAGTTAGACAATTTAAGGAA
ACAATTAAGAGCGATTCATCCTGAAATTCTTATTGCTGAAGATAACCCAGTCAATCGAATGCTTTTAAGTTCCCTCTTAC
AAGAACATGCCGCTATTGAACTAGTAGAAAATGGCGAGGAAACGCTTAGAGCTTGTCAAGAAAAACGCTATAATTTACTT
CTCTTAGACGTACAGATGCCTAAATTAAATGGACTAGAGGCCGCAAAATTAGTTCGCAAAGAATCTATTTTAAATCGAAG
AACGCCAATTGTTGTTATTAGTGCTAACACCAATGATGTCAAACAAGAGCAATTAACAAAATCAGGAATTGATCTTTGCT
TAGAAAAACCTATTGATGAAAAACAATTATTAACTCACCTCTTACGCATCCTTAATAAAACTAAAGCGCTTGCCATTGAT
TGGTCGCTTTGTGTGCAAAAAGTTTCTGGTAATCAAATTTTGGCAGAAGAATTTTTAACGCGCTTTGTAGAAGAACTTAC
TAAAAGTCAGCCTGAGTTTGTCACTTTATTTGAGCAAAAGGATATTAAAGGACTTGAAAGTGCAGCCCATAAGCTCAATG
GCGCCTGTTGTTTTTGTGGCGTACCTAGACTACAAAGTCAGGTCATTCGTCTTGAGAAAAAAGCCAAAGAAGCTAAAGAT
ATTGCCGCAATAAAAGAAGTTTTTGCTGAGTTTATGCAAAGTGCTGATGAAGTTATTAAAGAATTCGAAAATTTCTATCA
AGCAAAGTCTTTAAATTAG

Domains

Predicted by InterproScan.

• Hpt domain (Hpt) (817-880)

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Single cache domain 4 (sCache_4) (35-179)

• Response regulator receiver domain (Response_reg) (676-787)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	71.224	99.452	0.708