Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   ACNVED_RS06060 Genome accession   NZ_CP183303
Coordinates   1373427..1374752 (+) Length   441 a.a.
NCBI ID   WP_419420859.1    Uniprot ID   -
Organism   Legionella sp. D16C41     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1368427..1379752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNVED_RS06035 (ACNVED_06035) - 1368745..1368948 (+) 204 WP_419420855.1 hypothetical protein -
  ACNVED_RS06045 (ACNVED_06045) - 1369116..1369928 (-) 813 WP_419420856.1 polysaccharide deacetylase family protein -
  ACNVED_RS06050 (ACNVED_06050) - 1370382..1371422 (+) 1041 WP_419420857.1 YARHG domain-containing protein -
  ACNVED_RS06055 (ACNVED_06055) - 1371856..1373430 (+) 1575 WP_419420858.1 sensor histidine kinase -
  ACNVED_RS06060 (ACNVED_06060) pilR 1373427..1374752 (+) 1326 WP_419420859.1 sigma-54-dependent transcriptional regulator Regulator
  ACNVED_RS06065 (ACNVED_06065) - 1374845..1376263 (-) 1419 WP_419420860.1 M48 family metalloprotease -
  ACNVED_RS06070 (ACNVED_06070) ribD 1376521..1377600 (+) 1080 WP_419420861.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  ACNVED_RS06075 (ACNVED_06075) - 1377585..1378196 (+) 612 WP_419420862.1 riboflavin synthase -
  ACNVED_RS06080 (ACNVED_06080) ribB 1378198..1379403 (+) 1206 WP_419420863.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49628.49 Da        Isoelectric Point: 6.5086

>NTDB_id=1105173 ACNVED_RS06060 WP_419420859.1 1373427..1374752(+) (pilR) [Legionella sp. D16C41]
MIDKAHILVIDDEPDICELLSLTLVHMGYSCDLAYTYQQAIEKLNSNIYSLVLTDMRLPDGDGIELVKYIQKTKNQLPVA
VITAYGNVEGAVNTLKAGAFDYLSKPVDLKQLKDLVKTALLMQEKKEQAKDDVLLGKSTVMQELRQNIDKLARNQAPVFI
SGESGVGKELVAQLIHRQGPRAEKPFIPVNCGAIPNELLESEFFGHKKGSFTGAITDKVGLFVAANGGTLFLDEIAELSL
SMQVKLLRAIQEKAIKPIGEHSEIPVDIRLLSASHKNLQDEIMAGHFRQDLYYRVNVIELRVPTLRERLTDIPILTDYIL
SNLGRKQNRTILPLSRECIQKLQSYYFPGNVRELENILERAVAMCEGDTITIEEIQLPQAIPSAIGYQQFNSNLNDLLYE
HEKELILKTLEQTKWNRTAAAKLLGISFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1105173 ACNVED_RS06060 WP_419420859.1 1373427..1374752(+) (pilR) [Legionella sp. D16C41]
ATGATAGATAAAGCGCATATATTGGTTATAGATGATGAGCCTGATATTTGTGAATTGCTATCTCTTACTCTAGTACATAT
GGGGTATAGTTGTGATTTAGCATATACGTATCAGCAAGCCATCGAAAAGCTCAATAGTAATATTTATAGTTTGGTATTAA
CAGATATGCGTTTGCCAGATGGTGATGGAATTGAACTAGTTAAATATATTCAAAAAACTAAAAATCAACTTCCTGTTGCA
GTTATTACCGCTTACGGTAACGTTGAAGGAGCTGTAAATACTTTAAAAGCTGGTGCATTTGATTATTTATCGAAACCTGT
TGATTTAAAACAATTAAAAGACTTAGTTAAAACTGCTTTATTAATGCAAGAAAAAAAAGAGCAAGCTAAAGATGATGTTT
TATTAGGTAAAAGTACTGTGATGCAAGAGTTACGGCAGAATATTGATAAGTTGGCACGTAATCAAGCGCCGGTTTTCATT
TCAGGAGAATCTGGAGTAGGTAAAGAATTAGTTGCTCAGCTTATTCATCGTCAAGGCCCGCGTGCAGAAAAACCTTTTAT
TCCTGTTAACTGTGGTGCAATTCCCAATGAATTGCTAGAGTCTGAATTTTTTGGCCATAAAAAAGGCAGTTTTACTGGCG
CGATTACTGACAAGGTTGGACTTTTTGTTGCAGCCAATGGTGGAACCTTATTTCTTGATGAAATCGCTGAATTATCATTA
TCAATGCAAGTAAAATTATTAAGAGCGATTCAAGAGAAAGCTATTAAACCTATAGGCGAACATAGCGAAATTCCGGTTGA
TATTCGTTTACTTAGTGCAAGTCATAAAAATTTACAAGATGAAATCATGGCAGGCCATTTTCGCCAAGATCTCTATTATC
GGGTTAACGTTATAGAATTACGCGTACCAACACTTCGCGAACGGTTAACCGATATTCCAATACTAACAGATTATATATTA
AGCAATTTAGGCCGCAAACAAAACCGCACAATTTTGCCCTTATCACGAGAATGTATTCAAAAGCTACAAAGTTACTATTT
TCCAGGGAATGTACGTGAATTAGAAAATATTCTAGAAAGGGCGGTAGCGATGTGCGAAGGAGATACAATTACTATTGAAG
AAATTCAGTTGCCCCAAGCCATACCTTCCGCTATAGGATATCAACAATTTAATAGCAATTTAAATGATTTGCTGTATGAA
CATGAAAAAGAACTCATTCTTAAAACTTTAGAGCAAACTAAATGGAATCGTACTGCTGCGGCTAAACTCTTAGGCATAAG
TTTTCGTACGCTGCGGTATCGTTTAAAGAAATTAGGTTTAGACTAA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(134-300)

Response regulator receiver domain (Response_reg)

(7-116)

Bacterial regulatory protein, Fis family (HTH_8)

(401-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

57.366

100

0.583
  pilR Acinetobacter baumannii strain A118

46.352

100

0.49

Multiple sequence alignment