Detailed information NTG0110339

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HV97_RS17125
• Genome accession: NZ_CP008870
• Coordinates: 3640814..3643090 (-)
• Length: 758 a.a.
• NCBI ID: WP_003090432.1
• Uniprot ID: A0A0H2ZAW8
• Organism: Pseudomonas aeruginosa strain W36662
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3635814..3648090

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HV97_RS17105 (HV97_13610)	trxB	3637979..3638929 (+)	951	WP_003090421.1	thioredoxin-disulfide reductase	-
HV97_RS17110 (HV97_13615)	aat	3638967..3639647 (+)	681	WP_003113368.1	leucyl/phenylalanyl-tRNA--protein transferase	-
HV97_RS17115 (HV97_13620)	-	3639702..3640409 (+)	708	WP_003097644.1	arginyltransferase	-
HV97_RS17120 (HV97_13625)	infA	3640514..3640732 (+)	219	WP_002553999.1	translation initiation factor IF-1	-
HV97_RS17125 (HV97_13630)	clpC	3640814..3643090 (-)	2277	WP_003090432.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
HV97_RS17130 (HV97_13635)	clpS	3643118..3643486 (-)	369	WP_003097649.1	ATP-dependent Clp protease adapter ClpS	-
HV97_RS17135 (HV97_13640)	cspD	3643712..3643984 (+)	273	WP_023087246.1	cold shock domain-containing protein CspD	-
HV97_RS17140 (HV97_13645)	icd	3644057..3645313 (-)	1257	WP_003090436.1	NADP-dependent isocitrate dehydrogenase	-
HV97_RS17145 (HV97_13650)	-	3645672..3647897 (+)	2226	WP_003116719.1	NADP-dependent isocitrate dehydrogenase	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84010.68 Da
• Isoelectric Point: 5.8904

>NTDB_id=110339 HV97_RS17125 WP_003090432.1 3640814..3643090(-) (clpC) [Pseudomonas aeruginosa strain W36662]
MLNRELEVTLNLAFKEARAKRHEFMTVEHLLLALLDNEAAATVLRACGANLDKLRRDLQEFIDSTTPLIPQHDDERETQP
TLGFQRVLQRAVFHVQSSGKREVTGANVLVAIFSEQESQAVFLLKQQSIARIDVVNYIAHGISKVPGHAEHPQDGEQDMQ
DEEGGESATSNHPLDAYASNLNELARQGRIDPLVGREHEVERVAQILARRRKNNPLLVGEAGVGKTAIAEGLAKRIVDGQ
VPDLLADSVVYSLDLGALLAGTKYRGDFEKRFKALLNELRKRPHAVLFIDEIHTIIGAGAASGGVMDASNLLKPVLSSGE
IRCIGSTTFQEFRGIFEKDRALARRFQKVDVTEPSVEDTYGILKGLKGRFEQHHHIEYSDEALRAAAELAARYINDRHMP
DKAIDVIDEAGAYQRLQPEEKRVKRIEVAQVEDIVAKIARIPPKHVTTSDKELLRNLERDLKLTVFGQDDAIESLSTAIK
LSRAGLKAPDKPVGSFLFAGPTGVGKTEVARQLAKALGVELVRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTEAITK
TPHCVLLLDEIEKAHPEVFNLLLQVMDHGTLTDNNGRKADFRNIILIMTTNAGAEVAARASIGFNQQDHTTDAMEVIKKS
FTPEFRNRLDTIIQFGRLSTETIKSVVDKFLTELQAQLEDKRVQLEVSDAARGWLAEKGYDVQMGARPMARLIQDKIKRP
LAEEILFGELAEHGGLVHVDLKGDELAFEFEITAAEPA

Nucleotide

• Length: 2277 bp

>NTDB_id=110339 HV97_RS17125 WP_003090432.1 3640814..3643090(-) (clpC) [Pseudomonas aeruginosa strain W36662]
ATGTTGAATCGAGAGCTCGAAGTCACCCTCAATCTCGCCTTCAAGGAGGCGAGGGCCAAACGCCATGAATTCATGACGGT
TGAGCACCTGCTGCTGGCCTTGCTGGACAATGAGGCGGCGGCAACGGTATTGCGTGCGTGCGGTGCCAACCTGGACAAGC
TGCGGCGCGACCTGCAGGAATTCATCGATTCCACCACGCCGCTGATCCCGCAGCACGACGACGAGCGCGAAACCCAGCCG
ACGCTGGGCTTCCAGCGCGTCCTGCAGCGTGCGGTGTTCCACGTGCAGAGTTCCGGCAAGCGCGAAGTGACCGGGGCCAA
TGTCCTGGTGGCGATCTTCAGCGAACAGGAAAGCCAGGCGGTGTTCCTGCTCAAGCAGCAGAGCATCGCGCGTATCGATG
TGGTGAACTACATCGCCCATGGTATCTCCAAGGTGCCCGGGCATGCCGAACATCCGCAGGATGGGGAGCAGGATATGCAG
GATGAGGAAGGTGGCGAGTCGGCCACGTCCAACCATCCGCTGGACGCCTATGCCAGCAACCTCAACGAGCTGGCTCGCCA
GGGGCGGATCGACCCGCTGGTGGGGCGTGAGCATGAAGTCGAGCGGGTGGCGCAGATCCTTGCCCGCCGGCGCAAGAACA
ACCCGCTGCTGGTAGGCGAGGCGGGGGTCGGCAAGACGGCCATCGCCGAGGGCCTGGCCAAACGCATCGTCGATGGCCAG
GTGCCGGACCTGCTGGCCGACAGCGTGGTCTACTCCCTCGACCTGGGTGCCTTGCTCGCGGGTACCAAGTACCGCGGCGA
CTTCGAGAAGCGCTTCAAGGCCTTGCTCAACGAGTTGCGCAAGCGCCCGCACGCGGTGCTGTTCATCGACGAGATCCATA
CCATCATCGGCGCCGGTGCGGCATCCGGCGGGGTAATGGACGCCTCCAACCTGCTCAAGCCGGTTCTGTCCTCGGGCGAG
ATCCGCTGCATCGGCTCGACCACCTTCCAGGAGTTCCGCGGCATCTTCGAGAAGGACCGGGCCTTGGCGCGGCGCTTCCA
GAAGGTCGACGTGACCGAGCCGTCGGTGGAAGACACCTATGGCATCCTCAAGGGCCTCAAGGGGCGCTTCGAGCAGCATC
ACCACATCGAGTACAGCGACGAGGCGCTGCGCGCCGCGGCCGAGCTGGCGGCGCGCTACATCAACGACCGGCACATGCCG
GACAAGGCCATCGACGTCATCGACGAGGCGGGCGCCTACCAGCGCCTGCAGCCGGAAGAGAAGCGCGTGAAGCGCATCGA
GGTGGCGCAGGTCGAGGATATCGTGGCGAAGATTGCGCGGATCCCGCCGAAACACGTCACCACCTCCGACAAGGAGTTGC
TGCGCAACCTCGAACGCGACCTCAAGCTGACCGTGTTCGGCCAGGACGACGCCATCGAGTCGCTGTCCACGGCGATCAAG
CTGTCCCGGGCCGGGCTCAAGGCGCCGGACAAGCCGGTCGGCTCATTCCTCTTCGCCGGTCCCACCGGCGTGGGCAAGAC
CGAGGTGGCGCGGCAGTTGGCGAAGGCCTTGGGTGTGGAGCTGGTGCGCTTCGACATGTCCGAGTACATGGAGCGGCATA
CCGTGTCGCGGCTGATCGGTGCGCCTCCGGGCTACGTCGGCTTCGACCAGGGCGGCCTGCTCACCGAGGCGATCACCAAG
ACCCCGCACTGCGTGTTGCTGCTCGACGAGATCGAGAAGGCTCACCCGGAGGTCTTCAACCTGCTGCTGCAGGTGATGGA
CCACGGCACCCTGACCGACAACAACGGGCGCAAGGCGGACTTCCGCAACATCATCCTGATCATGACCACCAACGCCGGCG
CGGAAGTGGCGGCGCGCGCGTCGATCGGCTTCAACCAGCAGGATCACACCACCGATGCGATGGAAGTGATCAAGAAGAGC
TTCACCCCGGAGTTCCGCAACCGCCTGGATACCATCATCCAGTTCGGCCGCCTGAGCACCGAGACGATCAAGAGCGTGGT
CGACAAGTTCCTCACCGAGCTGCAGGCGCAGCTGGAGGACAAGCGCGTCCAGCTCGAGGTCAGCGATGCGGCGCGCGGCT
GGCTGGCGGAGAAGGGCTACGACGTGCAGATGGGTGCGCGACCGATGGCGCGGCTTATCCAGGACAAGATCAAGCGGCCG
TTGGCCGAGGAGATCCTGTTCGGCGAGCTGGCCGAGCATGGCGGCCTGGTGCATGTCGACCTGAAGGGCGACGAGCTGGC
CTTCGAGTTCGAGATCACGGCGGCGGAGCCCGCCTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (216-328)

• AAA lid domain (AAA_lid_9) (355-458)

• AAA domain (Cdc48 subfamily) (AAA_2) (491-652)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (658-739)

3D structure

• AlphaFold DB: A0A0H2ZAW8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	38.956	100	0.423
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.667	96.57	0.402
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.247	100	0.389
clpC	Streptococcus mutans UA159	45.484	81.794	0.372
clpC	Lactococcus lactis subsp. cremoris KW2	44.586	82.85	0.369