Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   ACMS1Y_RS16930 Genome accession   NZ_CP181431
Coordinates   3282456..3283631 (-) Length   391 a.a.
NCBI ID   WP_060698460.1    Uniprot ID   -
Organism   Bacillus safensis strain BS22LVI     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 3262193..3281487 3282456..3283631 flank 969


Gene organization within MGE regions


Location: 3262193..3283631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMS1Y_RS16815 - 3262193..3262612 (-) 420 WP_024423621.1 TIGR03826 family flagellar region protein -
  ACMS1Y_RS16820 comFC 3262669..3262824 (-) 156 WP_277722747.1 ComF family protein Machinery gene
  ACMS1Y_RS16825 - 3262836..3263324 (-) 489 WP_415316066.1 ComF family protein -
  ACMS1Y_RS16830 - 3263351..3263644 (-) 294 WP_254965333.1 late competence development ComFB family protein -
  ACMS1Y_RS16835 epsC 3263969..3264817 (-) 849 WP_254965332.1 serine O-acetyltransferase EpsC -
  ACMS1Y_RS16840 pyrH 3264918..3265658 (+) 741 WP_254965331.1 UMP kinase -
  ACMS1Y_RS16845 - 3265714..3266892 (-) 1179 WP_254965329.1 MFS transporter -
  ACMS1Y_RS16850 - 3266955..3267875 (-) 921 WP_254965327.1 phosphotransferase -
  ACMS1Y_RS16855 - 3267890..3269065 (-) 1176 WP_254965326.1 ATP-grasp domain-containing protein -
  ACMS1Y_RS16860 - 3269067..3270287 (-) 1221 WP_254965324.1 ATP-grasp domain-containing protein -
  ACMS1Y_RS16865 - 3270298..3271893 (-) 1596 WP_254965322.1 class I adenylate-forming enzyme family protein -
  ACMS1Y_RS16870 - 3271933..3272190 (-) 258 WP_254965320.1 acyl carrier protein -
  ACMS1Y_RS16875 - 3272187..3272489 (-) 303 WP_415316068.1 SDR family oxidoreductase -
  ACMS1Y_RS16880 - 3272504..3272908 (-) 405 WP_415316069.1 SDR family NAD(P)-dependent oxidoreductase -
  ACMS1Y_RS16885 - 3272909..3273877 (-) 969 WP_254965317.1 alpha/beta hydrolase -
  ACMS1Y_RS16890 - 3273882..3275399 (-) 1518 WP_254965315.1 NAD(P)-dependent oxidoreductase -
  ACMS1Y_RS16895 - 3275414..3276109 (-) 696 WP_254965312.1 hypothetical protein -
  ACMS1Y_RS16900 - 3276121..3276969 (-) 849 WP_254965310.1 NAD(P)-dependent oxidoreductase -
  ACMS1Y_RS16905 - 3276973..3278448 (-) 1476 WP_254965308.1 nucleoside monophosphate kinase -
  ACMS1Y_RS16910 - 3278445..3279557 (-) 1113 WP_254965306.1 nucleotidyltransferase family protein -
  ACMS1Y_RS16915 - 3279554..3279856 (-) 303 WP_254965304.1 Dabb family protein -
  ACMS1Y_RS16920 - 3280645..3281487 (-) 843 WP_254965302.1 DegV family protein -
  ACMS1Y_RS16925 degU 3281702..3282391 (-) 690 WP_008348273.1 two-component system response regulator DegU Regulator
  ACMS1Y_RS16930 degS 3282456..3283631 (-) 1176 WP_060698460.1 sensor histidine kinase Regulator

Sequence

Protein


Download         Length: 391 a.a.        Molecular weight: 45509.22 Da        Isoelectric Point: 5.8757

>NTDB_id=1100121 ACMS1Y_RS16930 WP_060698460.1 3282456..3283631(-) (degS) [Bacillus safensis strain BS22LVI]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTESERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLSLQNKIVK

Nucleotide


Download         Length: 1176 bp        

>NTDB_id=1100121 ACMS1Y_RS16930 WP_060698460.1 3282456..3283631(-) (degS) [Bacillus safensis strain BS22LVI]
ATGACAACACCCAAAATGGATCCGAAATTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGCAAGGA
CGAAGTATTTAGAATAGGCGAACAGTCCCGTCAACAATATGAAAGCCTAGTAGAAGAGCTCAAGCAAATCAAGCAGCAAG
TAAACGAAGTAATTGATTTTGGGGACAAGCTGGAAGTCCATACAAGACATGCTAGAAATCGCTTATCTGAGGTCAGCAGA
AACTTCAACAAATTCAGCGAAGAAGAAATACGTGAGGCCTACGAAAAAGCACATAACTTGCAAGTGGAACTTACCATGAT
CCAGCAGCGTGAGAAGCAGCTGAGAGAAAGAAGAGACGATCTGGAAAGACGATTATTAAGCTTACAAGACGTCATTGAGC
GTTCTGAAACGCTTGTGAGTCAGATTACAGTGGTTCTCAACTATCTCAACCAGGATTTACGCCAGGTCGGCGTTTTACTT
GAAGATGCTCAGGCAAAACAAGATTTTGGGCTGAGAATTATTGAAGCCCAAGAAGAAGAACGCAAAAGAGTGTCTCGGGA
AATTCATGACGGCCCTGCTCAAATGCTGGCAAACGTGATGATGCGTTCCGAATTAATTGAACGAATTTTTAGAGACCGCG
GTACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTCAGACAGAATGTGCGGAATGCACTGTACGAAGTGAGAAGAATAATT
TATGATTTAAGACCGATGGCTTTAGATGATTTGGGTTTGATTCCGACACTGAGAAAATACTTAAACACAATTGAAGAATA
TGATGGGAAAACCAAAATTACGTTCCAATGCCTAGGTGATACAGAAAGCGAAAGAATTGCTTCTCAATTTGAAGTAGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCATTAAAGCATTCTGAAGCTGAAGAAATCTCTGTCAAAGTAGAAGTA
ACGAAAGACTTTGTGACCTTAATTATTAAAGACGATGGAAAAGGCTTTGATATGAAAGATGTGAAAACAAACAAAAACAA
ATCCTTCGGTTTACTTGGCATGAAAGAACGCGTAGACTTACTGGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTTATCATGATTCGCGTGCCATTATCATTGCAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

Sensor protein DegS (DegS)

(12-170)

Histidine kinase (HisKA_3)

(180-248)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

85.714

98.465

0.844

Multiple sequence alignment