Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACLQ7P_RS06470 Genome accession   NZ_CP181322
Coordinates   1287962..1288618 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis subsp. subtilis strain JCK-1398     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1282962..1293618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLQ7P_RS06440 (ACLQ7P_06440) oppF 1283214..1284131 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACLQ7P_RS06445 (ACLQ7P_06445) yjbB 1284239..1285456 (+) 1218 WP_416247643.1 MFS transporter -
  ACLQ7P_RS06450 (ACLQ7P_06450) yjbC 1285620..1286198 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACLQ7P_RS06455 (ACLQ7P_06455) spx 1286379..1286774 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ACLQ7P_RS06460 (ACLQ7P_06460) yjbE 1287029..1287685 (-) 657 WP_014479447.1 TerC family protein -
  ACLQ7P_RS06465 (ACLQ7P_06465) - 1287855..1287995 (+) 141 WP_119122854.1 hypothetical protein -
  ACLQ7P_RS06470 (ACLQ7P_06470) mecA 1287962..1288618 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  ACLQ7P_RS06475 (ACLQ7P_06475) - 1288613..1288735 (-) 123 WP_021479547.1 hypothetical protein -
  ACLQ7P_RS06480 (ACLQ7P_06480) coiA 1288809..1289930 (+) 1122 WP_235091746.1 competence protein CoiA Machinery gene
  ACLQ7P_RS06485 (ACLQ7P_06485) pepF 1290160..1292013 (+) 1854 WP_326043354.1 oligoendopeptidase F -
  ACLQ7P_RS06490 (ACLQ7P_06490) - 1292027..1292194 (-) 168 WP_003244944.1 hypothetical protein -
  ACLQ7P_RS06495 (ACLQ7P_06495) spxH 1292508..1293407 (-) 900 WP_308153880.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=1099687 ACLQ7P_RS06470 WP_014479448.1 1287962..1288618(+) (mecA) [Bacillus subtilis subsp. subtilis strain JCK-1398]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1099687 ACLQ7P_RS06470 WP_014479448.1 1287962..1288618(+) (mecA) [Bacillus subtilis subsp. subtilis strain JCK-1398]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment