Detailed information NTG1099286

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACM6AO_RS04935
• Genome accession: NZ_CP181153
• Coordinates: 1002499..1003485 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AG21-0615
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 997499..1008485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AO_RS04910 (ACM6AO_04910)	opp4B	997713..998675 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACM6AO_RS04915 (ACM6AO_04915)	opp4C	998687..999568 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACM6AO_RS04920 (ACM6AO_04920)	trpS	999610..1000599 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACM6AO_RS04925 (ACM6AO_04925)	spxA	1000893..1001288 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACM6AO_RS04930 (ACM6AO_04930)	mecA	1001659..1002378 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACM6AO_RS04935 (ACM6AO_04935)	coiA	1002499..1003485 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACM6AO_RS04940 (ACM6AO_04940)	pepF	1003533..1005341 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACM6AO_RS04945 (ACM6AO_04945)	yjbH	1005801..1006607 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACM6AO_RS04950 (ACM6AO_04950)	-	1006630..1006995 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACM6AO_RS04955 (ACM6AO_04955)	-	1007099..1007692 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACM6AO_RS04960 (ACM6AO_04960)	-	1007878..1008225 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1099286 ACM6AO_RS04935 WP_000959282.1 1002499..1003485(+) (coiA) [Staphylococcus aureus strain AG21-0615]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1099286 ACM6AO_RS04935 WP_000959282.1 1002499..1003485(+) (coiA) [Staphylococcus aureus strain AG21-0615]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976