Detailed information NTG1099201

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACM6AP_RS04575
• Genome accession: NZ_CP181151
• Coordinates: 963471..964457 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AG21-0618
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 958471..969457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AP_RS04550 (ACM6AP_04550)	opp4B	958685..959647 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACM6AP_RS04555 (ACM6AP_04555)	opp4C	959659..960540 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACM6AP_RS04560 (ACM6AP_04560)	trpS	960582..961571 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACM6AP_RS04565 (ACM6AP_04565)	spxA	961865..962260 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACM6AP_RS04570 (ACM6AP_04570)	mecA	962631..963350 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACM6AP_RS04575 (ACM6AP_04575)	coiA	963471..964457 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACM6AP_RS04580 (ACM6AP_04580)	pepF	964505..966313 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACM6AP_RS04585 (ACM6AP_04585)	yjbH	966773..967579 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACM6AP_RS04590 (ACM6AP_04590)	-	967602..967967 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACM6AP_RS04595 (ACM6AP_04595)	-	968071..968664 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACM6AP_RS04600 (ACM6AP_04600)	-	968850..969197 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1099201 ACM6AP_RS04575 WP_000959282.1 963471..964457(+) (coiA) [Staphylococcus aureus strain AG21-0618]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1099201 ACM6AP_RS04575 WP_000959282.1 963471..964457(+) (coiA) [Staphylococcus aureus strain AG21-0618]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976