Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACM6AC_RS02500 Genome accession   NZ_CP181150
Coordinates   538773..539342 (+) Length   189 a.a.
NCBI ID   WP_000872876.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0600     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 533773..544342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AC_RS02475 (ACM6AC_02475) cysE 534986..535633 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  ACM6AC_RS02480 (ACM6AC_02480) cysS 535617..537017 (+) 1401 WP_154284090.1 cysteine--tRNA ligase -
  ACM6AC_RS02485 (ACM6AC_02485) - 537010..537414 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  ACM6AC_RS02490 (ACM6AC_02490) rlmB 537422..538168 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACM6AC_RS02495 (ACM6AC_02495) - 538168..538692 (+) 525 WP_000664740.1 NYN domain-containing protein -
  ACM6AC_RS02500 (ACM6AC_02500) sigH 538773..539342 (+) 570 WP_000872876.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACM6AC_RS02505 (ACM6AC_02505) rpmG 539457..539600 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACM6AC_RS02510 (ACM6AC_02510) secE 539656..539838 (+) 183 WP_031785167.1 preprotein translocase subunit SecE -
  ACM6AC_RS02515 (ACM6AC_02515) nusG 539851..540399 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACM6AC_RS02520 (ACM6AC_02520) rplK 540580..541002 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACM6AC_RS02525 (ACM6AC_02525) rplA 541210..541902 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACM6AC_RS02530 (ACM6AC_02530) rplJ 542174..542674 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACM6AC_RS02535 (ACM6AC_02535) rplL 542717..543085 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACM6AC_RS02540 (ACM6AC_02540) - 543260..543868 (+) 609 WP_000020305.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.96 Da        Isoelectric Point: 9.6015

>NTDB_id=1099153 ACM6AC_RS02500 WP_000872876.1 538773..539342(+) (sigH) [Staphylococcus aureus strain AG21-0600]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1099153 ACM6AC_RS02500 WP_000872876.1 538773..539342(+) (sigH) [Staphylococcus aureus strain AG21-0600]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

99.471

100

0.995
  sigH Staphylococcus aureus N315

98.413

100

0.984

Multiple sequence alignment