Detailed information NTG1099033

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACM6AW_RS04685
• Genome accession: NZ_CP181145
• Coordinates: 963510..964496 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AG21-0629
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 958510..969496

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AW_RS04660 (ACM6AW_04660)	opp4B	958724..959686 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACM6AW_RS04665 (ACM6AW_04665)	opp4C	959698..960579 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACM6AW_RS04670 (ACM6AW_04670)	trpS	960621..961610 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACM6AW_RS04675 (ACM6AW_04675)	spxA	961904..962299 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACM6AW_RS04680 (ACM6AW_04680)	mecA	962670..963389 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACM6AW_RS04685 (ACM6AW_04685)	coiA	963510..964496 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACM6AW_RS04690 (ACM6AW_04690)	pepF	964544..966352 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACM6AW_RS04695 (ACM6AW_04695)	yjbH	966812..967618 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACM6AW_RS04700 (ACM6AW_04700)	-	967641..968006 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACM6AW_RS04705 (ACM6AW_04705)	-	968110..968703 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACM6AW_RS04710 (ACM6AW_04710)	-	968889..969236 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1099033 ACM6AW_RS04685 WP_000959282.1 963510..964496(+) (coiA) [Staphylococcus aureus strain AG21-0629]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1099033 ACM6AW_RS04685 WP_000959282.1 963510..964496(+) (coiA) [Staphylococcus aureus strain AG21-0629]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976