Detailed information NTG1098989

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACM6AX_RS04690
• Genome accession: NZ_CP181142
• Coordinates: 965030..966016 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AG21-0630
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 960030..971016

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AX_RS04665 (ACM6AX_04665)	opp4B	960244..961206 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACM6AX_RS04670 (ACM6AX_04670)	opp4C	961218..962099 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACM6AX_RS04675 (ACM6AX_04675)	trpS	962141..963130 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACM6AX_RS04680 (ACM6AX_04680)	spxA	963424..963819 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACM6AX_RS04685 (ACM6AX_04685)	mecA	964190..964909 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACM6AX_RS04690 (ACM6AX_04690)	coiA	965030..966016 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACM6AX_RS04695 (ACM6AX_04695)	pepF	966064..967872 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACM6AX_RS04700 (ACM6AX_04700)	yjbH	968332..969138 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACM6AX_RS04705 (ACM6AX_04705)	-	969161..969526 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACM6AX_RS04710 (ACM6AX_04710)	-	969630..970223 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACM6AX_RS04715 (ACM6AX_04715)	-	970409..970756 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1098989 ACM6AX_RS04690 WP_000959282.1 965030..966016(+) (coiA) [Staphylococcus aureus strain AG21-0630]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1098989 ACM6AX_RS04690 WP_000959282.1 965030..966016(+) (coiA) [Staphylococcus aureus strain AG21-0630]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976