Detailed information NTG1098903

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACM6AD_RS04925
• Genome accession: NZ_CP181138
• Coordinates: 1003229..1004215 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AG21-0601
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 998229..1009215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AD_RS04900 (ACM6AD_04900)	opp4B	998443..999405 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACM6AD_RS04905 (ACM6AD_04905)	opp4C	999417..1000298 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACM6AD_RS04910 (ACM6AD_04910)	trpS	1000340..1001329 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACM6AD_RS04915 (ACM6AD_04915)	spxA	1001623..1002018 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACM6AD_RS04920 (ACM6AD_04920)	mecA	1002389..1003108 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACM6AD_RS04925 (ACM6AD_04925)	coiA	1003229..1004215 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACM6AD_RS04930 (ACM6AD_04930)	pepF	1004263..1006071 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACM6AD_RS04935 (ACM6AD_04935)	yjbH	1006531..1007337 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACM6AD_RS04940 (ACM6AD_04940)	-	1007360..1007725 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACM6AD_RS04945 (ACM6AD_04945)	-	1007829..1008422 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACM6AD_RS04950 (ACM6AD_04950)	-	1008608..1008955 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1098903 ACM6AD_RS04925 WP_000959282.1 1003229..1004215(+) (coiA) [Staphylococcus aureus strain AG21-0601]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1098903 ACM6AD_RS04925 WP_000959282.1 1003229..1004215(+) (coiA) [Staphylococcus aureus strain AG21-0601]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976