Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACM6AQ_RS09195 Genome accession   NZ_CP181136
Coordinates   1880787..1881416 (-) Length   209 a.a.
NCBI ID   WP_072491830.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0619     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1875787..1886416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AQ_RS09165 (ACM6AQ_09165) - 1876207..1876737 (-) 531 WP_000184381.1 acyl-CoA thioesterase -
  ACM6AQ_RS09170 (ACM6AQ_09170) - 1876827..1878083 (-) 1257 WP_001793428.1 aminopeptidase -
  ACM6AQ_RS09175 (ACM6AQ_09175) - 1878086..1878286 (-) 201 WP_000180460.1 DUF1128 family protein -
  ACM6AQ_RS09180 (ACM6AQ_09180) - 1878433..1878897 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  ACM6AQ_RS09185 (ACM6AQ_09185) - 1878904..1879179 (+) 276 WP_072491832.1 YtxH domain-containing protein -
  ACM6AQ_RS09190 (ACM6AQ_09190) - 1879457..1880674 (+) 1218 WP_072491831.1 YihY/virulence factor BrkB family protein -
  ACM6AQ_RS09195 (ACM6AQ_09195) vraR 1880787..1881416 (-) 630 WP_072491830.1 two-component system response regulator VraR Regulator
  ACM6AQ_RS09200 (ACM6AQ_09200) vraS 1881406..1882449 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  ACM6AQ_RS09205 (ACM6AQ_09205) liaF 1882446..1883147 (-) 702 WP_098818122.1 cell wall-active antibiotics response protein LiaF -
  ACM6AQ_RS09210 (ACM6AQ_09210) - 1883162..1883548 (-) 387 WP_001110179.1 hypothetical protein -
  ACM6AQ_RS09215 (ACM6AQ_09215) map 1883765..1884523 (-) 759 WP_061732059.1 type I methionyl aminopeptidase -
  ACM6AQ_RS09220 (ACM6AQ_09220) - 1884990..1885976 (+) 987 WP_000999713.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23575.38 Da        Isoelectric Point: 5.3889

>NTDB_id=1098879 ACM6AQ_RS09195 WP_072491830.1 1880787..1881416(-) (vraR) [Staphylococcus aureus strain AG21-0619]
MTIKVLFVDDHEMVRIGISSYLSMQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1098879 ACM6AQ_RS09195 WP_072491830.1 1880787..1881416(-) (vraR) [Staphylococcus aureus strain AG21-0619]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAATGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment