Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACM6AQ_RS02555 Genome accession   NZ_CP181136
Coordinates   531190..531759 (+) Length   189 a.a.
NCBI ID   WP_210994134.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0619     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 526190..536759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AQ_RS02530 (ACM6AQ_02530) cysE 527370..528050 (+) 681 WP_106875299.1 serine O-acetyltransferase -
  ACM6AQ_RS02535 (ACM6AQ_02535) cysS 528034..529434 (+) 1401 WP_072491339.1 cysteine--tRNA ligase -
  ACM6AQ_RS02540 (ACM6AQ_02540) - 529427..529831 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  ACM6AQ_RS02545 (ACM6AQ_02545) rlmB 529839..530585 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACM6AQ_RS02550 (ACM6AQ_02550) - 530585..531109 (+) 525 WP_106875298.1 NYN domain-containing protein -
  ACM6AQ_RS02555 (ACM6AQ_02555) sigH 531190..531759 (+) 570 WP_210994134.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACM6AQ_RS02560 (ACM6AQ_02560) rpmG 531874..532017 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACM6AQ_RS02565 (ACM6AQ_02565) secE 532073..532255 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACM6AQ_RS02570 (ACM6AQ_02570) nusG 532268..532816 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACM6AQ_RS02575 (ACM6AQ_02575) rplK 532997..533419 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACM6AQ_RS02580 (ACM6AQ_02580) rplA 533627..534319 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACM6AQ_RS02585 (ACM6AQ_02585) rplJ 534591..535091 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACM6AQ_RS02590 (ACM6AQ_02590) rplL 535134..535502 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACM6AQ_RS02595 (ACM6AQ_02595) - 535677..536285 (+) 609 WP_000020308.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23069.90 Da        Isoelectric Point: 9.4995

>NTDB_id=1098850 ACM6AQ_RS02555 WP_210994134.1 531190..531759(+) (sigH) [Staphylococcus aureus strain AG21-0619]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIQMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1098850 ACM6AQ_RS02555 WP_210994134.1 531190..531759(+) (sigH) [Staphylococcus aureus strain AG21-0619]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACAGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAAAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment