Detailed information NTG1098646

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACM6AE_RS04955
• Genome accession: NZ_CP181124
• Coordinates: 1008170..1009156 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AG21-0604
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1003170..1014156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AE_RS04930 (ACM6AE_04930)	opp4B	1003384..1004346 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACM6AE_RS04935 (ACM6AE_04935)	opp4C	1004358..1005239 (+)	882	WP_416152713.1	oligopeptide ABC transporter permease	-
ACM6AE_RS04940 (ACM6AE_04940)	trpS	1005281..1006270 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACM6AE_RS04945 (ACM6AE_04945)	spxA	1006564..1006959 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACM6AE_RS04950 (ACM6AE_04950)	mecA	1007330..1008049 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACM6AE_RS04955 (ACM6AE_04955)	coiA	1008170..1009156 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACM6AE_RS04960 (ACM6AE_04960)	pepF	1009204..1011012 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACM6AE_RS04965 (ACM6AE_04965)	yjbH	1011472..1012278 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACM6AE_RS04970 (ACM6AE_04970)	-	1012301..1012666 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACM6AE_RS04975 (ACM6AE_04975)	-	1012770..1013363 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACM6AE_RS04980 (ACM6AE_04980)	-	1013549..1013896 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1098646 ACM6AE_RS04955 WP_000959282.1 1008170..1009156(+) (coiA) [Staphylococcus aureus strain AG21-0604]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1098646 ACM6AE_RS04955 WP_000959282.1 1008170..1009156(+) (coiA) [Staphylococcus aureus strain AG21-0604]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976