Detailed information NTG1098515

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACM6AH_RS04950
• Genome accession: NZ_CP181115
• Coordinates: 1003658..1004644 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AG21-0608
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 998658..1009644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AH_RS04925 (ACM6AH_04925)	opp4B	998872..999834 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACM6AH_RS04930 (ACM6AH_04930)	opp4C	999846..1000727 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACM6AH_RS04935 (ACM6AH_04935)	trpS	1000769..1001758 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACM6AH_RS04940 (ACM6AH_04940)	spxA	1002052..1002447 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACM6AH_RS04945 (ACM6AH_04945)	mecA	1002818..1003537 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACM6AH_RS04950 (ACM6AH_04950)	coiA	1003658..1004644 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACM6AH_RS04955 (ACM6AH_04955)	pepF	1004692..1006500 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACM6AH_RS04960 (ACM6AH_04960)	yjbH	1006960..1007766 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACM6AH_RS04965 (ACM6AH_04965)	-	1007789..1008154 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACM6AH_RS04970 (ACM6AH_04970)	-	1008258..1008851 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACM6AH_RS04975 (ACM6AH_04975)	-	1009037..1009384 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1098515 ACM6AH_RS04950 WP_000959282.1 1003658..1004644(+) (coiA) [Staphylococcus aureus strain AG21-0608]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1098515 ACM6AH_RS04950 WP_000959282.1 1003658..1004644(+) (coiA) [Staphylococcus aureus strain AG21-0608]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976