Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ABXG87_RS07055 Genome accession   NZ_AP031488
Coordinates   1515360..1516586 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain NBRC 13956     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1505601..1514467 1515360..1516586 flank 893


Gene organization within MGE regions


Location: 1505601..1516586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXG87_RS07005 - 1505601..1506143 (-) 543 WP_118057898.1 hypothetical protein -
  ABXG87_RS07010 (Ssa13956_13170) parE 1506299..1508248 (-) 1950 WP_045768973.1 DNA topoisomerase IV subunit B -
  ABXG87_RS07015 (Ssa13956_13180) plsY 1508386..1509027 (+) 642 WP_353551333.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  ABXG87_RS07020 (Ssa13956_13190) - 1509143..1509520 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  ABXG87_RS07025 (Ssa13956_13200) - 1509595..1509849 (-) 255 WP_002886199.1 DUF1912 family protein -
  ABXG87_RS07030 (Ssa13956_13210) mmuM 1509962..1510912 (-) 951 WP_070850201.1 homocysteine S-methyltransferase -
  ABXG87_RS07035 (Ssa13956_13220) - 1510924..1512300 (-) 1377 WP_070850203.1 amino acid permease -
  ABXG87_RS07040 - 1512430..1512513 (-) 84 Protein_1333 YihA family ribosome biogenesis GTP-binding protein -
  ABXG87_RS07045 (Ssa13956_13230) - 1512506..1514467 (-) 1962 WP_070850274.1 retron Ec67 family RNA-directed DNA polymerase/endonuclease -
  ABXG87_RS07050 (Ssa13956_13240) yihA 1514751..1515350 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ABXG87_RS07055 (Ssa13956_13250) clpX 1515360..1516586 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=109806 ABXG87_RS07055 WP_002890340.1 1515360..1516586(-) (clpX) [Streptococcus salivarius strain NBRC 13956]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=109806 ABXG87_RS07055 WP_002890340.1 1515360..1516586(-) (clpX) [Streptococcus salivarius strain NBRC 13956]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCTTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACCGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGAAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCTGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGAATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTTTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATCCAAAAATTTGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTGGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTTA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCTGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment