Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACGHT2_RS06450 Genome accession   NZ_AP031455
Coordinates   1211247..1212476 (-) Length   409 a.a.
NCBI ID   WP_003065195.1    Uniprot ID   A0AAW6Y801
Organism   Streptococcus pasteurianus strain k46-0107-A9     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1163190..1214116 1211247..1212476 within 0


Gene organization within MGE regions


Location: 1163190..1214116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGHT2_RS06160 - 1163664..1163828 (+) 165 WP_003065096.1 TetR/AcrR family transcriptional regulator -
  ACGHT2_RS06165 (K460107A9_11310) - 1164338..1164760 (-) 423 WP_058692264.1 hypothetical protein -
  ACGHT2_RS06170 (K460107A9_11320) - 1164757..1165230 (-) 474 WP_058692263.1 Panacea domain-containing protein -
  ACGHT2_RS06175 (K460107A9_11330) - 1165411..1165551 (-) 141 WP_155589450.1 hypothetical protein -
  ACGHT2_RS06180 (K460107A9_11340) - 1165754..1166440 (-) 687 Protein_1153 GH25 family lysozyme -
  ACGHT2_RS06185 (K460107A9_11350) - 1166427..1166753 (-) 327 WP_390578117.1 phage holin -
  ACGHT2_RS06190 (K460107A9_11360) - 1166750..1166944 (-) 195 WP_230321680.1 hypothetical protein -
  ACGHT2_RS06195 (K460107A9_11370) - 1167044..1167217 (-) 174 WP_012961516.1 hypothetical protein -
  ACGHT2_RS06200 (K460107A9_11380) - 1167207..1167692 (-) 486 WP_390578119.1 hypothetical protein -
  ACGHT2_RS06205 (K460107A9_11390) - 1167689..1167868 (-) 180 WP_390578121.1 hypothetical protein -
  ACGHT2_RS06210 (K460107A9_11400) - 1167870..1172912 (-) 5043 WP_390578123.1 phage tail protein -
  ACGHT2_RS06215 (K460107A9_11410) - 1172924..1173763 (-) 840 WP_390578125.1 phage tail domain-containing protein -
  ACGHT2_RS06220 (K460107A9_11420) - 1173775..1178256 (-) 4482 WP_390578127.1 phage tail tape measure protein -
  ACGHT2_RS06225 (K460107A9_11430) - 1178276..1178443 (-) 168 WP_214224641.1 hypothetical protein -
  ACGHT2_RS06230 (K460107A9_11440) - 1178581..1179045 (-) 465 WP_390578129.1 tail assembly chaperone -
  ACGHT2_RS06235 (K460107A9_11450) - 1179107..1179682 (-) 576 WP_117575611.1 phage major tail protein, TP901-1 family -
  ACGHT2_RS06240 (K460107A9_11460) - 1179702..1180061 (-) 360 WP_117567209.1 hypothetical protein -
  ACGHT2_RS06245 (K460107A9_11470) - 1180069..1180413 (-) 345 WP_117575608.1 HK97-gp10 family putative phage morphogenesis protein -
  ACGHT2_RS06250 (K460107A9_11480) - 1180410..1180688 (-) 279 WP_117575606.1 hypothetical protein -
  ACGHT2_RS06255 (K460107A9_11490) - 1180685..1181041 (-) 357 WP_259293870.1 phage head-tail connector protein -
  ACGHT2_RS06260 (K460107A9_11500) - 1181050..1181943 (-) 894 WP_101774137.1 phage capsid protein -
  ACGHT2_RS06265 (K460107A9_11510) - 1181947..1182522 (-) 576 WP_117575602.1 DUF4355 domain-containing protein -
  ACGHT2_RS06270 (K460107A9_11520) - 1182906..1184297 (-) 1392 WP_390578133.1 minor capsid protein -
  ACGHT2_RS06275 (K460107A9_11530) - 1184278..1185783 (-) 1506 WP_259293869.1 phage portal protein -
  ACGHT2_RS06280 (K460107A9_11540) - 1185792..1187078 (-) 1287 WP_117575596.1 PBSX family phage terminase large subunit -
  ACGHT2_RS06285 (K460107A9_11550) - 1187065..1187490 (-) 426 WP_240208095.1 terminase small subunit -
  ACGHT2_RS06290 (K460107A9_11560) - 1187883..1188296 (-) 414 WP_253042041.1 transcriptional regulator -
  ACGHT2_RS06295 (K460107A9_11570) - 1188989..1189222 (-) 234 WP_390578136.1 hypothetical protein -
  ACGHT2_RS06300 (K460107A9_11580) - 1189212..1189451 (-) 240 WP_117567239.1 hypothetical protein -
  ACGHT2_RS06305 (K460107A9_11590) - 1189460..1189855 (-) 396 WP_270627711.1 RusA family crossover junction endodeoxyribonuclease -
  ACGHT2_RS06310 (K460107A9_11600) - 1189848..1190342 (-) 495 WP_390578139.1 DUF1642 domain-containing protein -
  ACGHT2_RS06315 (K460107A9_11610) - 1190630..1192903 (-) 2274 WP_390578141.1 AAA family ATPase -
  ACGHT2_RS06320 (K460107A9_11620) - 1192920..1194503 (-) 1584 WP_390578143.1 DEAD/DEAH box helicase -
  ACGHT2_RS06325 (K460107A9_11630) - 1194514..1195095 (-) 582 WP_390578145.1 hypothetical protein -
  ACGHT2_RS06330 (K460107A9_11640) - 1195124..1196209 (-) 1086 WP_390578147.1 ATP-binding protein -
  ACGHT2_RS06335 (K460107A9_11650) - 1196209..1196544 (-) 336 WP_077496283.1 hypothetical protein -
  ACGHT2_RS06340 (K460107A9_11660) - 1196564..1197859 (-) 1296 WP_390578149.1 AAA family ATPase -
  ACGHT2_RS06345 (K460107A9_11670) - 1197843..1198085 (-) 243 WP_117567261.1 hypothetical protein -
  ACGHT2_RS06350 (K460107A9_11680) - 1198082..1198300 (-) 219 WP_214240579.1 hypothetical protein -
  ACGHT2_RS06355 (K460107A9_11690) - 1198302..1198454 (-) 153 WP_162261893.1 hypothetical protein -
  ACGHT2_RS06360 (K460107A9_11700) - 1198451..1198762 (-) 312 WP_390578152.1 excisionase -
  ACGHT2_RS06365 (K460107A9_11710) - 1198921..1199145 (+) 225 WP_240208056.1 hypothetical protein -
  ACGHT2_RS06370 (K460107A9_11720) - 1199127..1199279 (-) 153 WP_240208055.1 hypothetical protein -
  ACGHT2_RS06375 (K460107A9_11730) - 1199475..1199684 (-) 210 WP_128116674.1 helix-turn-helix transcriptional regulator -
  ACGHT2_RS06380 (K460107A9_11740) - 1199744..1200427 (+) 684 WP_195990928.1 DUF4145 domain-containing protein -
  ACGHT2_RS06385 (K460107A9_11760) - 1200875..1201657 (+) 783 WP_195990930.1 S24 family peptidase -
  ACGHT2_RS06390 (K460107A9_11770) - 1201669..1202196 (+) 528 WP_247909227.1 hypothetical protein -
  ACGHT2_RS06395 - 1202220..1202336 (+) 117 WP_390578156.1 colicin immunity protein -
  ACGHT2_RS06400 (K460107A9_11780) - 1202436..1202693 (+) 258 WP_348634460.1 MazG-like protein -
  ACGHT2_RS06405 (K460107A9_11790) - 1202898..1203713 (+) 816 WP_154455270.1 NYN domain-containing protein -
  ACGHT2_RS06410 (K460107A9_11800) - 1203847..1204998 (+) 1152 WP_058692220.1 site-specific integrase -
  ACGHT2_RS06415 (K460107A9_11810) rplL 1205099..1205467 (-) 369 WP_003065188.1 50S ribosomal protein L7/L12 -
  ACGHT2_RS06420 (K460107A9_11820) rplJ 1205537..1206040 (-) 504 WP_003065189.1 50S ribosomal protein L10 -
  ACGHT2_RS06425 (K460107A9_11830) - 1206568..1208676 (+) 2109 WP_270619557.1 AAA family ATPase -
  ACGHT2_RS06430 (K460107A9_11840) - 1208782..1209429 (+) 648 WP_048791465.1 endonuclease III domain-containing protein -
  ACGHT2_RS06435 (K460107A9_11850) - 1209538..1210206 (+) 669 WP_048791487.1 YoaK family protein -
  ACGHT2_RS06440 - 1210296..1210511 (-) 216 WP_082144682.1 GyrI-like domain-containing protein -
  ACGHT2_RS06445 (K460107A9_11860) yihA 1210643..1211239 (-) 597 WP_048791466.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACGHT2_RS06450 (K460107A9_11870) clpX 1211247..1212476 (-) 1230 WP_003065195.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACGHT2_RS06455 (K460107A9_11880) - 1212509..1212679 (-) 171 WP_003065196.1 hypothetical protein -
  ACGHT2_RS06460 (K460107A9_11890) - 1212695..1213189 (-) 495 WP_048791467.1 dihydrofolate reductase -
  ACGHT2_RS06465 (K460107A9_11900) - 1213277..1214116 (-) 840 WP_270619556.1 thymidylate synthase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45140.74 Da        Isoelectric Point: 4.5644

>NTDB_id=109617 ACGHT2_RS06450 WP_003065195.1 1211247..1212476(-) (clpX) [Streptococcus pasteurianus strain k46-0107-A9]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQDR
AKRALAVAVYNHYKRVSFAESRNEEDVDLQKSNILMIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDENASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDKDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSQEEVTKVRVTKAAVEG
KDKPILEIA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=109617 ACGHT2_RS06450 WP_003065195.1 1211247..1212476(-) (clpX) [Streptococcus pasteurianus strain k46-0107-A9]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTCTGTGGAAAAAGCCAAGATGAAGTGAAAAAAATCAT
TGCAGGAAACAATGTTTTTATCTGTAATGAGTGCGTGGCTTTGTCACAAGAAATTATCAAAGAAGAACTTGCTGAAGAAG
TTCTTGCAGATTTAGCGGAAGTTCCAAAACCTAAAGAGTTGTTAGCAACTCTTGACGAATATGTCGTTGGTCAAGACCGT
GCCAAACGCGCGCTTGCCGTAGCTGTTTATAACCATTACAAACGTGTTTCTTTTGCGGAAAGTCGCAACGAAGAAGATGT
TGATTTGCAAAAATCAAACATTTTGATGATTGGTCCTACAGGTTCAGGAAAAACATTCCTAGCTCAAACTTTGGCTAAAA
CATTGAATGTACCGTTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGATGTTGAAAATATC
CTTTTGAAATTAATTCAAGCAGCTGATTTTAATATCGAACGCGCAGAACGCGGTATCATTTACGTGGACGAAATTGATAA
AATCGCTAAAAAAGGCGAAAATGTCTCAATTACACGTGATGTTTCAGGTGAAGGTGTTCAACAAGCACTTCTTAAAATCA
TTGAAGGAACAGTTGCTAGCGTACCACCTCAAGGTGGACGTAAGCACCCTAACCAAGAAATGATTCAAATTGATACTAAA
AATATCCTATTCATTGTCGGCGGTGCTTTTGATGGTATCGAGGATATTGTCAAACAACGTTTAGGTGAAAAGGTTATCGG
TTTTGGCCAAAATAACCGTAAAATTGATGAAAATGCTTCTTATATGCAAGAAATCATTTCAGAAGATATTCAAAAATTTG
GCTTGATTCCAGAGTTTATCGGACGTTTGCCAGTTGTAGCGGCACTTGAACAGTTGACGGCTGATGATTTGGTTCGTATC
TTGACAGAACCACGTAATGCCTTGGTTAAACAATATCAAACACTATTATCATATGACGGTGTTGAACTAGAATTTGATAA
AGATGCTTTGCAAGCTATTGCTAACAAAGCCATTGAACGTAAGACAGGAGCTCGTGGTTTACGCTCAATTATTGAGGAAA
CTATGATGGATATCATGTTTGAAATTCCTAGCCAAGAAGAAGTGACCAAGGTTCGTGTCACTAAAGCGGCTGTTGAAGGC
AAAGATAAACCAATTTTGGAAATTGCGTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.731

100

0.897
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.354

98.044

0.572

Multiple sequence alignment