Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACLHDE_RS12345 Genome accession   NZ_CP180409
Coordinates   2435031..2436833 (+) Length   600 a.a.
NCBI ID   WP_415396716.1    Uniprot ID   -
Organism   Sulfurimonas sp. CS5     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2430031..2441833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLHDE_RS12325 (ACLHDE_12320) nhaD 2431642..2433021 (-) 1380 WP_415396712.1 sodium:proton antiporter NhaD -
  ACLHDE_RS12330 (ACLHDE_12325) nadB 2433018..2434466 (-) 1449 WP_415396713.1 L-aspartate oxidase -
  ACLHDE_RS12335 (ACLHDE_12330) - 2434466..2434621 (-) 156 WP_415396714.1 hypothetical protein -
  ACLHDE_RS12340 (ACLHDE_12335) - 2434712..2435041 (+) 330 WP_415396715.1 hypothetical protein -
  ACLHDE_RS12345 (ACLHDE_12340) uvrC 2435031..2436833 (+) 1803 WP_415396716.1 excinuclease ABC subunit UvrC Machinery gene
  ACLHDE_RS12350 (ACLHDE_12345) - 2436900..2437313 (+) 414 WP_415396717.1 PAS domain-containing protein -
  ACLHDE_RS12355 (ACLHDE_12350) - 2437323..2438942 (+) 1620 WP_415396718.1 Hpt domain-containing protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69298.12 Da        Isoelectric Point: 9.6852

>NTDB_id=1095742 ACLHDE_RS12345 WP_415396716.1 2435031..2436833(+) (uvrC) [Sulfurimonas sp. CS5]
MTLKQTIKQLPDSAGIYQYFDKNGHLLYIGKAKSLQKRVKSYFNFAPELKANANLSLRITKMINQTESMNYIVVKSEHDA
LILENSLIKQLNPKYNILLRDDKTYPYIYIDNSQKYPRFEITRKIIKASDINYFGPFSVGARDILDSVYELCKLVQKKGS
LKSKKLCLYHQIDKCLGPCELPISEARYKRELDLAYELIQNKKLLVKKLQEKMSFYAENLRFEEAGAIRDRIEKISRSEI
KSEIDFATNENYDIFVLQNSSLRAVVVRIFMRDGKIISSTHDYIQLNEGYDEDELYQRVLLDFYRSEKPPIIAPILVASE
FENLQVIEEHLSSVFEKKANIKVPKQGNKKQLIDLAILNAKELLKRDKNSHDTQVLEDLKELLSLERIPKRVEVFDNSHM
SGVATVGAMIVYEDGKFDKKSYRTYHLQAKDEYAQMRETLTRRVESFSKNSPPDLWIIDGGATLLKLASDIVDSAGVFID
IIAISKEKIDAKAHRAKGKANDIIHTKNDIFRLKNSDKRLQWTQNLRDEAHRSAIGFHKKTKLKLDKESKLLNLHGISEA
KVKKLLNHFGTFEALKTLTLEEINSVLNIKDAIVIKNIYF

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1095742 ACLHDE_RS12345 WP_415396716.1 2435031..2436833(+) (uvrC) [Sulfurimonas sp. CS5]
ATGACTCTTAAACAAACGATAAAACAGCTTCCTGACTCTGCTGGCATCTATCAGTATTTTGACAAAAATGGGCATCTGCT
TTACATAGGAAAAGCTAAGAGTCTGCAAAAAAGAGTAAAAAGCTACTTTAACTTTGCACCTGAGCTAAAAGCAAATGCTA
ATCTTTCACTTAGAATAACTAAAATGATAAACCAAACTGAGTCTATGAACTACATAGTTGTAAAGTCAGAACACGATGCT
CTTATACTCGAAAACTCACTGATAAAGCAATTAAATCCTAAGTATAATATTCTCCTTCGTGATGATAAAACCTATCCTTA
CATCTATATAGACAACTCTCAAAAATATCCAAGATTTGAGATTACAAGAAAAATAATAAAAGCTTCTGATATTAACTATT
TTGGCCCCTTTTCTGTTGGTGCTAGAGATATTTTAGATTCTGTTTATGAGCTATGTAAACTTGTGCAAAAAAAAGGATCT
TTAAAGTCAAAAAAACTATGTCTATACCATCAGATAGATAAATGTTTAGGTCCTTGTGAGCTACCCATCTCTGAAGCAAG
ATATAAGCGAGAGTTGGATTTAGCGTATGAACTTATTCAGAACAAAAAACTATTGGTAAAAAAACTTCAAGAAAAAATGT
CTTTTTATGCTGAAAACTTAAGGTTTGAAGAGGCAGGAGCAATTAGAGACAGAATCGAGAAAATATCTCGTTCTGAGATT
AAAAGCGAGATTGATTTTGCAACAAATGAGAACTACGATATTTTTGTACTTCAAAACTCATCTTTAAGAGCTGTTGTGGT
TAGAATATTTATGAGAGATGGAAAGATTATATCATCTACCCACGACTATATTCAATTGAATGAAGGGTATGATGAAGACG
AGCTTTATCAAAGAGTTCTGCTAGATTTTTATAGAAGTGAAAAACCTCCGATAATAGCACCTATCTTAGTAGCGTCAGAG
TTTGAAAACTTACAAGTCATTGAGGAGCATCTCAGTAGTGTGTTTGAAAAAAAAGCTAATATTAAAGTGCCAAAACAGGG
AAATAAAAAGCAGTTAATAGACTTAGCAATCTTAAATGCCAAAGAGCTTCTAAAAAGAGATAAAAACTCTCACGACACAC
AAGTTTTAGAAGATTTAAAAGAGCTGCTCTCTTTAGAACGCATTCCTAAAAGAGTAGAAGTTTTTGATAATTCACATATG
TCAGGAGTGGCAACTGTTGGAGCTATGATAGTTTATGAGGATGGAAAGTTTGATAAAAAAAGTTACAGAACTTATCATCT
TCAAGCAAAAGATGAATACGCTCAGATGCGAGAGACTCTAACAAGAAGAGTTGAGAGTTTTTCTAAAAACTCCCCGCCAG
ACTTATGGATTATAGATGGTGGAGCTACACTTTTAAAACTGGCATCTGATATTGTAGATTCAGCAGGTGTTTTTATAGAC
ATCATTGCTATTTCTAAAGAAAAGATTGATGCAAAGGCTCATCGAGCAAAAGGTAAAGCAAATGATATTATTCATACTAA
GAATGATATTTTTAGATTGAAAAATTCTGACAAAAGACTCCAGTGGACACAAAATCTAAGGGATGAAGCTCACAGAAGTG
CGATTGGTTTTCATAAAAAGACCAAATTAAAACTCGATAAAGAGAGTAAACTTCTAAACCTTCATGGAATCTCTGAAGCA
AAAGTGAAAAAACTACTCAATCATTTTGGAACATTTGAAGCTCTAAAAACCTTAACTCTAGAAGAAATAAATTCCGTTTT
AAATATAAAAGATGCGATAGTAATTAAAAATATTTACTTCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(380-535)

GIY-YIG catalytic domain (GIY-YIG)

(15-96)

UvrB/uvrC motif (UVR)

(205-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.767

97.833

0.497

Multiple sequence alignment