Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | ACMVYK_RS02320 | Genome accession | NZ_CP180313 |
| Coordinates | 467588..468163 (+) | Length | 191 a.a. |
| NCBI ID | WP_001829272.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain YSMAS1_1_E3 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 468700..504460 | 467588..468163 | flank | 537 |
Gene organization within MGE regions
Location: 467588..504460
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACMVYK_RS02320 (ACMVYK_02320) | comK/comK1 | 467588..468163 (+) | 576 | WP_001829272.1 | competence protein ComK | Regulator |
| ACMVYK_RS02335 (ACMVYK_02335) | - | 468700..469764 (-) | 1065 | WP_002491600.1 | site-specific integrase | - |
| ACMVYK_RS02340 (ACMVYK_02340) | - | 469841..470515 (-) | 675 | WP_049392317.1 | Ltp family lipoprotein | - |
| ACMVYK_RS02345 (ACMVYK_02345) | - | 470528..470902 (-) | 375 | WP_002501701.1 | hypothetical protein | - |
| ACMVYK_RS02350 (ACMVYK_02350) | - | 471058..471393 (-) | 336 | WP_002446811.1 | helix-turn-helix domain-containing protein | - |
| ACMVYK_RS02355 (ACMVYK_02355) | - | 471554..471745 (+) | 192 | WP_002501702.1 | helix-turn-helix transcriptional regulator | - |
| ACMVYK_RS02360 (ACMVYK_02360) | - | 471799..472107 (+) | 309 | WP_002501703.1 | DUF771 domain-containing protein | - |
| ACMVYK_RS02365 (ACMVYK_02365) | - | 472592..472786 (+) | 195 | WP_002491611.1 | DUF1270 family protein | - |
| ACMVYK_RS02370 (ACMVYK_02370) | - | 472934..474175 (+) | 1242 | WP_002501705.1 | SNF2-related protein | - |
| ACMVYK_RS02375 (ACMVYK_02375) | - | 474178..474495 (+) | 318 | WP_002501706.1 | hypothetical protein | - |
| ACMVYK_RS02380 (ACMVYK_02380) | - | 474488..474784 (+) | 297 | WP_002484599.1 | hypothetical protein | - |
| ACMVYK_RS02385 (ACMVYK_02385) | - | 474784..476595 (+) | 1812 | WP_002501707.1 | AAA family ATPase | - |
| ACMVYK_RS02390 (ACMVYK_02390) | - | 476614..476820 (+) | 207 | WP_002501708.1 | hypothetical protein | - |
| ACMVYK_RS02395 (ACMVYK_02395) | - | 476872..477354 (+) | 483 | WP_002501709.1 | DUF669 domain-containing protein | - |
| ACMVYK_RS02400 (ACMVYK_02400) | - | 477404..479122 (+) | 1719 | WP_002501710.1 | hypothetical protein | - |
| ACMVYK_RS02405 (ACMVYK_02405) | - | 479206..479370 (+) | 165 | WP_002486494.1 | DUF3310 domain-containing protein | - |
| ACMVYK_RS02410 (ACMVYK_02410) | - | 479378..479767 (+) | 390 | WP_002501711.1 | hypothetical protein | - |
| ACMVYK_RS02415 (ACMVYK_02415) | - | 479775..480470 (-) | 696 | WP_002501712.1 | hypothetical protein | - |
| ACMVYK_RS02420 (ACMVYK_02420) | - | 480536..480838 (+) | 303 | WP_002501713.1 | MazG-like family protein | - |
| ACMVYK_RS02425 (ACMVYK_02425) | - | 480856..481071 (-) | 216 | WP_002491630.1 | hypothetical protein | - |
| ACMVYK_RS02430 (ACMVYK_02430) | - | 481143..481388 (+) | 246 | WP_002501714.1 | hypothetical protein | - |
| ACMVYK_RS02435 (ACMVYK_02435) | - | 481467..481661 (+) | 195 | WP_002501715.1 | hypothetical protein | - |
| ACMVYK_RS02440 (ACMVYK_02440) | - | 481691..483565 (+) | 1875 | WP_002501716.1 | phage/plasmid primase, P4 family | - |
| ACMVYK_RS02445 (ACMVYK_02445) | - | 483889..484380 (+) | 492 | WP_002501717.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| ACMVYK_RS02450 (ACMVYK_02450) | - | 484584..485195 (+) | 612 | WP_002501718.1 | hypothetical protein | - |
| ACMVYK_RS02455 (ACMVYK_02455) | - | 485478..485768 (+) | 291 | WP_002501719.1 | HNH endonuclease | - |
| ACMVYK_RS02460 (ACMVYK_02460) | - | 486088..486426 (+) | 339 | WP_002501720.1 | hypothetical protein | - |
| ACMVYK_RS02465 (ACMVYK_02465) | - | 486410..488044 (+) | 1635 | WP_002501721.1 | terminase TerL endonuclease subunit | - |
| ACMVYK_RS02470 (ACMVYK_02470) | - | 488060..489196 (+) | 1137 | WP_002501722.1 | phage portal protein | - |
| ACMVYK_RS02475 (ACMVYK_02475) | - | 489196..489942 (+) | 747 | WP_002501723.1 | head maturation protease, ClpP-related | - |
| ACMVYK_RS02480 (ACMVYK_02480) | - | 489967..491124 (+) | 1158 | WP_415405177.1 | phage major capsid protein | - |
| ACMVYK_RS02485 (ACMVYK_02485) | - | 491151..491459 (+) | 309 | WP_002484579.1 | phage head-tail connector protein | - |
| ACMVYK_RS02490 (ACMVYK_02490) | - | 491534..491761 (+) | 228 | WP_415405179.1 | phage head closure protein | - |
| ACMVYK_RS02495 (ACMVYK_02495) | - | 491761..492099 (+) | 339 | WP_002501726.1 | hypothetical protein | - |
| ACMVYK_RS02500 (ACMVYK_02500) | - | 492099..492536 (+) | 438 | WP_002501727.1 | hypothetical protein | - |
| ACMVYK_RS02505 (ACMVYK_02505) | - | 492542..493246 (+) | 705 | WP_002484613.1 | hypothetical protein | - |
| ACMVYK_RS02510 (ACMVYK_02510) | - | 493270..493614 (+) | 345 | WP_002501729.1 | hypothetical protein | - |
| ACMVYK_RS02515 (ACMVYK_02515) | - | 493668..493880 (+) | 213 | WP_032606956.1 | hypothetical protein | - |
| ACMVYK_RS02520 (ACMVYK_02520) | - | 493944..498125 (+) | 4182 | WP_415405182.1 | phage tail tape measure protein | - |
| ACMVYK_RS02525 (ACMVYK_02525) | - | 498128..498898 (+) | 771 | WP_049392193.1 | tail protein | - |
| ACMVYK_RS02530 (ACMVYK_02530) | - | 498895..502350 (+) | 3456 | WP_002501734.1 | phage tail spike protein | - |
| ACMVYK_RS02535 (ACMVYK_02535) | - | 502371..502781 (+) | 411 | WP_002501735.1 | hypothetical protein | - |
| ACMVYK_RS02540 (ACMVYK_02540) | - | 502818..503099 (+) | 282 | WP_002501736.1 | hypothetical protein | - |
| ACMVYK_RS02545 (ACMVYK_02545) | - | 503101..503487 (+) | 387 | WP_002446772.1 | phage holin family protein | - |
| ACMVYK_RS02550 (ACMVYK_02550) | - | 503540..504460 (+) | 921 | WP_002501737.1 | N-acetylmuramoyl-L-alanine amidase family protein | - |
Sequence
Protein
Download Length: 191 a.a. Molecular weight: 22782.87 Da Isoelectric Point: 9.2887
>NTDB_id=1095180 ACMVYK_RS02320 WP_001829272.1 467588..468163(+) (comK/comK1) [Staphylococcus epidermidis strain YSMAS1_1_E3]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
Nucleotide
Download Length: 576 bp
>NTDB_id=1095180 ACMVYK_RS02320 WP_001829272.1 467588..468163(+) (comK/comK1) [Staphylococcus epidermidis strain YSMAS1_1_E3]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
76.757 |
96.859 |
0.743 |
| comK/comK1 | Staphylococcus aureus N315 |
76.757 |
96.859 |
0.743 |