Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | ACMVYO_RS11020 | Genome accession | NZ_CP180296 |
| Coordinates | 2191213..2191797 (-) | Length | 194 a.a. |
| NCBI ID | WP_017175793.1 | Uniprot ID | A0A4V2KX31 |
| Organism | Staphylococcus hominis strain YSMAS1_1_D4 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 2149730..2190718 | 2191213..2191797 | flank | 495 |
Gene organization within MGE regions
Location: 2149730..2191797
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACMVYO_RS10730 (ACMVYO_10730) | - | 2149730..2150782 (-) | 1053 | WP_053028102.1 | tyrosine-type recombinase/integrase | - |
| ACMVYO_RS10735 (ACMVYO_10735) | - | 2150847..2151734 (-) | 888 | WP_053028103.1 | hypothetical protein | - |
| ACMVYO_RS10740 (ACMVYO_10740) | - | 2151803..2152885 (-) | 1083 | WP_415400814.1 | DUF5067 domain-containing protein | - |
| ACMVYO_RS10745 (ACMVYO_10745) | - | 2152908..2153366 (-) | 459 | WP_053028105.1 | ImmA/IrrE family metallo-endopeptidase | - |
| ACMVYO_RS10750 (ACMVYO_10750) | - | 2153379..2153705 (-) | 327 | WP_053028106.1 | helix-turn-helix domain-containing protein | - |
| ACMVYO_RS10755 (ACMVYO_10755) | - | 2153924..2154121 (+) | 198 | WP_053028107.1 | helix-turn-helix domain-containing protein | - |
| ACMVYO_RS10760 (ACMVYO_10760) | - | 2154182..2154895 (+) | 714 | WP_053028108.1 | ORF6C domain-containing protein | - |
| ACMVYO_RS10765 (ACMVYO_10765) | - | 2154897..2155211 (+) | 315 | WP_053028109.1 | DUF771 domain-containing protein | - |
| ACMVYO_RS10770 (ACMVYO_10770) | - | 2155231..2155401 (+) | 171 | WP_195832905.1 | hypothetical protein | - |
| ACMVYO_RS10775 (ACMVYO_10775) | - | 2155487..2155750 (+) | 264 | WP_053028110.1 | hypothetical protein | - |
| ACMVYO_RS10780 (ACMVYO_10780) | - | 2155753..2157702 (+) | 1950 | WP_415400818.1 | AAA family ATPase | - |
| ACMVYO_RS10785 (ACMVYO_10785) | - | 2157704..2158627 (+) | 924 | WP_063280508.1 | recombinase RecT | - |
| ACMVYO_RS10790 (ACMVYO_10790) | - | 2158708..2159325 (+) | 618 | WP_415401543.1 | MBL fold metallo-hydrolase | - |
| ACMVYO_RS10795 (ACMVYO_10795) | ssbA | 2159326..2159790 (+) | 465 | WP_415400820.1 | single-stranded DNA-binding protein | Machinery gene |
| ACMVYO_RS10800 (ACMVYO_10800) | - | 2159805..2160008 (+) | 204 | WP_347132297.1 | helix-turn-helix transcriptional regulator | - |
| ACMVYO_RS10805 (ACMVYO_10805) | - | 2160056..2160199 (+) | 144 | WP_415400822.1 | XRE family transcriptional regulator | - |
| ACMVYO_RS10810 (ACMVYO_10810) | - | 2160234..2161130 (+) | 897 | WP_415400824.1 | DnaD domain-containing protein | - |
| ACMVYO_RS10815 (ACMVYO_10815) | - | 2161123..2161347 (+) | 225 | WP_415400826.1 | hypothetical protein | - |
| ACMVYO_RS10820 (ACMVYO_10820) | - | 2161350..2161715 (+) | 366 | WP_415400828.1 | hypothetical protein | - |
| ACMVYO_RS10825 (ACMVYO_10825) | - | 2161708..2161926 (+) | 219 | WP_071560911.1 | hypothetical protein | - |
| ACMVYO_RS10830 (ACMVYO_10830) | - | 2161907..2162212 (+) | 306 | WP_019835309.1 | hypothetical protein | - |
| ACMVYO_RS10835 (ACMVYO_10835) | - | 2162205..2162459 (+) | 255 | WP_415400830.1 | hypothetical protein | - |
| ACMVYO_RS10840 (ACMVYO_10840) | dut | 2162440..2162862 (+) | 423 | WP_219045233.1 | dUTP diphosphatase | - |
| ACMVYO_RS10845 (ACMVYO_10845) | - | 2162912..2163157 (+) | 246 | WP_016064881.1 | hypothetical protein | - |
| ACMVYO_RS10850 (ACMVYO_10850) | - | 2163163..2163441 (+) | 279 | WP_415400833.1 | hypothetical protein | - |
| ACMVYO_RS10855 (ACMVYO_10855) | rinB | 2163434..2163616 (+) | 183 | WP_415400835.1 | transcriptional activator RinB | - |
| ACMVYO_RS10860 (ACMVYO_10860) | - | 2163885..2164382 (+) | 498 | WP_415400837.1 | Holliday junction resolvase RecU | - |
| ACMVYO_RS10865 (ACMVYO_10865) | - | 2164382..2164807 (+) | 426 | WP_019835317.1 | hypothetical protein | - |
| ACMVYO_RS10870 (ACMVYO_10870) | - | 2164960..2165769 (+) | 810 | WP_415400839.1 | hypothetical protein | - |
| ACMVYO_RS10875 (ACMVYO_10875) | - | 2165845..2166270 (+) | 426 | WP_016064888.1 | terminase small subunit | - |
| ACMVYO_RS10880 (ACMVYO_10880) | - | 2166273..2167562 (+) | 1290 | WP_415400841.1 | PBSX family phage terminase large subunit | - |
| ACMVYO_RS10885 (ACMVYO_10885) | - | 2167563..2169014 (+) | 1452 | WP_415400843.1 | phage portal protein | - |
| ACMVYO_RS10890 (ACMVYO_10890) | - | 2168998..2170035 (+) | 1038 | WP_053028131.1 | minor capsid protein | - |
| ACMVYO_RS10895 (ACMVYO_10895) | - | 2170028..2170177 (+) | 150 | WP_019835322.1 | hypothetical protein | - |
| ACMVYO_RS10900 (ACMVYO_10900) | - | 2170313..2170924 (+) | 612 | WP_415400846.1 | DUF4355 domain-containing protein | - |
| ACMVYO_RS10905 (ACMVYO_10905) | - | 2170940..2171851 (+) | 912 | WP_415400848.1 | capsid protein | - |
| ACMVYO_RS10910 (ACMVYO_10910) | - | 2171878..2172216 (+) | 339 | WP_415400850.1 | phage head-tail connector protein | - |
| ACMVYO_RS10915 (ACMVYO_10915) | - | 2172213..2172527 (+) | 315 | WP_415400852.1 | hypothetical protein | - |
| ACMVYO_RS10920 (ACMVYO_10920) | - | 2172517..2172867 (+) | 351 | WP_017175551.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| ACMVYO_RS10925 (ACMVYO_10925) | - | 2172878..2173273 (+) | 396 | WP_037541254.1 | hypothetical protein | - |
| ACMVYO_RS10930 (ACMVYO_10930) | - | 2173288..2173881 (+) | 594 | WP_019835328.1 | phage major tail protein, TP901-1 family | - |
| ACMVYO_RS10935 (ACMVYO_10935) | - | 2173950..2174321 (+) | 372 | WP_016064899.1 | tail assembly chaperone | - |
| ACMVYO_RS10940 (ACMVYO_10940) | - | 2174351..2174716 (+) | 366 | WP_017175548.1 | hypothetical protein | - |
| ACMVYO_RS10945 (ACMVYO_10945) | - | 2174716..2178108 (+) | 3393 | WP_415400855.1 | hypothetical protein | - |
| ACMVYO_RS10950 (ACMVYO_10950) | - | 2178121..2179077 (+) | 957 | WP_415400857.1 | phage tail domain-containing protein | - |
| ACMVYO_RS10955 (ACMVYO_10955) | - | 2179087..2180331 (+) | 1245 | WP_415400859.1 | phage tail protein | - |
| ACMVYO_RS10960 (ACMVYO_10960) | - | 2180342..2182216 (+) | 1875 | WP_415400861.1 | M14 family metallopeptidase | - |
| ACMVYO_RS10965 (ACMVYO_10965) | - | 2182229..2183425 (+) | 1197 | WP_415400863.1 | BppU family phage baseplate upper protein | - |
| ACMVYO_RS10970 (ACMVYO_10970) | - | 2183447..2183938 (+) | 492 | WP_002500204.1 | holin family protein | - |
| ACMVYO_RS10975 (ACMVYO_10975) | - | 2183988..2185925 (+) | 1938 | WP_415400865.1 | glucosaminidase domain-containing protein | - |
| ACMVYO_RS10980 (ACMVYO_10980) | - | 2185978..2187324 (+) | 1347 | WP_415400867.1 | BppU family phage baseplate upper protein | - |
| ACMVYO_RS10985 (ACMVYO_10985) | - | 2187338..2187682 (+) | 345 | WP_415400869.1 | hypothetical protein | - |
| ACMVYO_RS10990 (ACMVYO_10990) | - | 2187675..2187818 (+) | 144 | WP_019835340.1 | XkdX family protein | - |
| ACMVYO_RS10995 (ACMVYO_10995) | - | 2187873..2188172 (+) | 300 | WP_048681864.1 | hypothetical protein | - |
| ACMVYO_RS11000 (ACMVYO_11000) | - | 2188172..2189881 (+) | 1710 | WP_415400872.1 | N-acetylmuramoyl-L-alanine amidase family protein | - |
| ACMVYO_RS11005 (ACMVYO_11005) | - | 2190122..2190286 (+) | 165 | Protein_2117 | DNA-binding protein | - |
| ACMVYO_RS11020 (ACMVYO_11020) | comK/comK1 | 2191213..2191797 (-) | 585 | WP_017175793.1 | competence protein ComK | Regulator |
Sequence
Protein
Download Length: 194 a.a. Molecular weight: 22941.26 Da Isoelectric Point: 9.5206
>NTDB_id=1095138 ACMVYO_RS11020 WP_017175793.1 2191213..2191797(-) (comK/comK1) [Staphylococcus hominis strain YSMAS1_1_D4]
MTQFNKPPNTIYVIRKGDMVIRPTFDDHQQPNGSEILKFDTSREISPFKTQKIIERSCRFYGNNYLSKKAETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENIWINMHYISDIKPLKNRKSKIIFANQEALTLNVSFHSLWHQYSNSIFYYYMIDKQ
ARMKSNNPDMPIDYEKTSLNIFEALSHYSLLEDK
MTQFNKPPNTIYVIRKGDMVIRPTFDDHQQPNGSEILKFDTSREISPFKTQKIIERSCRFYGNNYLSKKAETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENIWINMHYISDIKPLKNRKSKIIFANQEALTLNVSFHSLWHQYSNSIFYYYMIDKQ
ARMKSNNPDMPIDYEKTSLNIFEALSHYSLLEDK
Nucleotide
Download Length: 585 bp
>NTDB_id=1095138 ACMVYO_RS11020 WP_017175793.1 2191213..2191797(-) (comK/comK1) [Staphylococcus hominis strain YSMAS1_1_D4]
ATGACTCAGTTCAATAAACCTCCTAATACGATTTATGTCATACGTAAAGGTGATATGGTGATTAGACCTACATTTGACGA
TCATCAACAACCGAACGGCTCAGAAATCCTCAAATTCGATACCTCACGAGAAATAAGTCCTTTTAAAACTCAAAAAATTA
TTGAACGATCTTGTAGATTTTATGGCAATAACTACTTAAGCAAGAAAGCTGAAACTCAACGCATTGCTGGAATAACTAGT
AAACCTCCCATCCTTCTCACACCATTGTTTCCAACTTACTTTTTCCCAACACATTCAGACCGTTTAGAAGAAAATATATG
GATTAATATGCATTATATTTCTGATATTAAGCCATTAAAAAACAGAAAGAGTAAAATTATCTTTGCAAATCAAGAAGCAC
TAACATTAAATGTATCTTTTCATAGTTTATGGCATCAATATTCTAATTCTATTTTCTATTACTATATGATTGATAAACAA
GCAAGAATGAAATCTAATAATCCAGATATGCCAATCGATTATGAAAAAACATCTTTAAATATTTTTGAGGCACTTTCACA
CTATTCTTTATTAGAAGATAAATAG
ATGACTCAGTTCAATAAACCTCCTAATACGATTTATGTCATACGTAAAGGTGATATGGTGATTAGACCTACATTTGACGA
TCATCAACAACCGAACGGCTCAGAAATCCTCAAATTCGATACCTCACGAGAAATAAGTCCTTTTAAAACTCAAAAAATTA
TTGAACGATCTTGTAGATTTTATGGCAATAACTACTTAAGCAAGAAAGCTGAAACTCAACGCATTGCTGGAATAACTAGT
AAACCTCCCATCCTTCTCACACCATTGTTTCCAACTTACTTTTTCCCAACACATTCAGACCGTTTAGAAGAAAATATATG
GATTAATATGCATTATATTTCTGATATTAAGCCATTAAAAAACAGAAAGAGTAAAATTATCTTTGCAAATCAAGAAGCAC
TAACATTAAATGTATCTTTTCATAGTTTATGGCATCAATATTCTAATTCTATTTTCTATTACTATATGATTGATAAACAA
GCAAGAATGAAATCTAATAATCCAGATATGCCAATCGATTATGAAAAAACATCTTTAAATATTTTTGAGGCACTTTCACA
CTATTCTTTATTAGAAGATAAATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
74.457 |
94.845 |
0.706 |
| comK/comK1 | Staphylococcus aureus N315 |
74.457 |
94.845 |
0.706 |