Detailed information    

insolico Bioinformatically predicted

Overview

Name   degU   Type   Regulator
Locus tag   ACLCDX_RS16960 Genome accession   NZ_CP180263
Coordinates   3284168..3284857 (-) Length   229 a.a.
NCBI ID   WP_008348273.1    Uniprot ID   A0A5K1NCW2
Organism   Bacillus safensis strain BS22LVI     
Function   activation of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 3264659..3283953 3284168..3284857 flank 215


Gene organization within MGE regions


Location: 3264659..3284857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLCDX_RS16850 (ACLCDX_16850) - 3264659..3265078 (-) 420 WP_024423621.1 TIGR03826 family flagellar region protein -
  ACLCDX_RS16855 (ACLCDX_16855) comFC 3265135..3265290 (-) 156 WP_277722747.1 ComF family protein Machinery gene
  ACLCDX_RS16860 (ACLCDX_16860) - 3265302..3265790 (-) 489 WP_415316066.1 ComF family protein -
  ACLCDX_RS16865 (ACLCDX_16865) - 3265817..3266110 (-) 294 WP_254965333.1 late competence development ComFB family protein -
  ACLCDX_RS16870 (ACLCDX_16870) epsC 3266435..3267283 (-) 849 WP_254965332.1 serine O-acetyltransferase EpsC -
  ACLCDX_RS16875 (ACLCDX_16875) pyrH 3267384..3268124 (+) 741 WP_254965331.1 UMP kinase -
  ACLCDX_RS16880 (ACLCDX_16880) - 3268180..3269358 (-) 1179 WP_254965329.1 MFS transporter -
  ACLCDX_RS16885 (ACLCDX_16885) - 3269421..3270341 (-) 921 WP_254965327.1 phosphotransferase -
  ACLCDX_RS16890 (ACLCDX_16890) - 3270356..3271531 (-) 1176 WP_254965326.1 ATP-grasp domain-containing protein -
  ACLCDX_RS16895 (ACLCDX_16895) - 3271533..3272753 (-) 1221 WP_254965324.1 ATP-grasp domain-containing protein -
  ACLCDX_RS16900 (ACLCDX_16900) - 3272764..3274359 (-) 1596 WP_254965322.1 class I adenylate-forming enzyme family protein -
  ACLCDX_RS16905 (ACLCDX_16905) - 3274399..3274656 (-) 258 WP_254965320.1 acyl carrier protein -
  ACLCDX_RS16910 (ACLCDX_16910) - 3274653..3274955 (-) 303 WP_415316068.1 SDR family oxidoreductase -
  ACLCDX_RS16915 (ACLCDX_16915) - 3274970..3275374 (-) 405 WP_415316069.1 SDR family NAD(P)-dependent oxidoreductase -
  ACLCDX_RS16920 (ACLCDX_16920) - 3275375..3276343 (-) 969 WP_254965317.1 alpha/beta hydrolase -
  ACLCDX_RS16925 (ACLCDX_16925) - 3276348..3277865 (-) 1518 WP_254965315.1 NAD(P)-dependent oxidoreductase -
  ACLCDX_RS16930 (ACLCDX_16930) - 3277880..3278575 (-) 696 WP_254965312.1 hypothetical protein -
  ACLCDX_RS16935 (ACLCDX_16935) - 3278587..3279435 (-) 849 WP_254965310.1 NAD(P)-dependent oxidoreductase -
  ACLCDX_RS16940 (ACLCDX_16940) - 3279439..3280914 (-) 1476 WP_254965308.1 nucleoside monophosphate kinase -
  ACLCDX_RS16945 (ACLCDX_16945) - 3280911..3282023 (-) 1113 WP_254965306.1 nucleotidyltransferase family protein -
  ACLCDX_RS16950 (ACLCDX_16950) - 3282020..3282322 (-) 303 WP_254965304.1 Dabb family protein -
  ACLCDX_RS16955 (ACLCDX_16955) - 3283111..3283953 (-) 843 WP_254965302.1 DegV family protein -
  ACLCDX_RS16960 (ACLCDX_16960) degU 3284168..3284857 (-) 690 WP_008348273.1 two-component system response regulator DegU Regulator

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 25852.54 Da        Isoelectric Point: 5.9436

>NTDB_id=1094994 ACLCDX_RS16960 WP_008348273.1 3284168..3284857(-) (degU) [Bacillus safensis strain BS22LVI]
MTKVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARIVEHYHPDVVIMDINMPNVNGVEATKQLVELYPESKV
IILSIHDDENYVTHALKTGARGYLLKEMDADTLIEAVKVVADGGSYLHPKVTHNLVNEFRRLATSGVSAHPQHEVYPEIR
RPLHILTRRECEVLQMLADGKSNRGIGESLFISEKTVKNHVSNILQKMNVNDRTQAVVVAIKNGWVEMR

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1094994 ACLCDX_RS16960 WP_008348273.1 3284168..3284857(-) (degU) [Bacillus safensis strain BS22LVI]
GTGACTAAAGTAAATATTGTAATTATTGATGACCACCAATTATTCCGTGAAGGTGTCAAACGGATTTTAGATTTTGAACC
TACTTTTGAAGTAGTTGCAGAAGGAGACGACGGTGACGAAGCTGCACGTATCGTAGAACACTATCATCCAGATGTTGTCA
TTATGGACATTAATATGCCGAATGTAAATGGTGTTGAGGCTACAAAGCAGCTTGTTGAGCTTTATCCCGAATCAAAAGTC
ATTATTCTATCTATTCATGACGATGAAAACTATGTAACACATGCATTGAAAACAGGGGCGAGAGGCTACCTGTTAAAAGA
AATGGATGCAGACACACTCATCGAAGCAGTGAAAGTTGTAGCTGACGGAGGCTCTTATTTACATCCGAAAGTCACTCATA
ATTTAGTAAATGAATTCCGACGCTTGGCAACCAGCGGCGTTTCAGCACATCCACAGCATGAGGTATATCCTGAAATTCGC
AGACCACTTCATATCTTAACTAGACGTGAATGTGAAGTTCTTCAAATGTTAGCTGACGGAAAGAGCAACAGAGGAATCGG
TGAATCGCTCTTTATTAGTGAGAAAACAGTCAAAAACCACGTGAGTAACATTTTGCAAAAAATGAATGTAAACGACCGTA
CACAAGCTGTTGTTGTAGCTATTAAAAACGGCTGGGTAGAAATGAGATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(165-220)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5K1NCW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degU Bacillus subtilis subsp. subtilis str. 168

99.563

100

0.996

Multiple sequence alignment