Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACL6EQ_RS05260 Genome accession   NZ_CP178716
Coordinates   1033273..1033929 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis strain SY1483     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1028273..1038929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL6EQ_RS05230 (ACL6EQ_05230) oppF 1028527..1029444 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACL6EQ_RS05235 (ACL6EQ_05235) yjbB 1029550..1030767 (+) 1218 WP_153255904.1 MFS transporter -
  ACL6EQ_RS05240 (ACL6EQ_05240) yjbC 1030931..1031509 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACL6EQ_RS05245 (ACL6EQ_05245) spx 1031690..1032085 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ACL6EQ_RS05250 (ACL6EQ_05250) yjbE 1032340..1032996 (-) 657 WP_003232944.1 TerC family protein -
  ACL6EQ_RS05255 (ACL6EQ_05255) - 1033166..1033306 (+) 141 WP_119122854.1 hypothetical protein -
  ACL6EQ_RS05260 (ACL6EQ_05260) mecA 1033273..1033929 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  ACL6EQ_RS05265 (ACL6EQ_05265) - 1033924..1034046 (-) 123 WP_003245684.1 hypothetical protein -
  ACL6EQ_RS05270 (ACL6EQ_05270) coiA 1034090..1035241 (+) 1152 WP_413360413.1 competence protein CoiA Machinery gene
  ACL6EQ_RS05275 (ACL6EQ_05275) pepF 1035471..1037300 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  ACL6EQ_RS05280 (ACL6EQ_05280) - 1037338..1037505 (-) 168 WP_003244944.1 hypothetical protein -
  ACL6EQ_RS05285 (ACL6EQ_05285) spxH 1037820..1038719 (-) 900 WP_024573348.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=1090752 ACL6EQ_RS05260 WP_003245194.1 1033273..1033929(+) (mecA) [Bacillus subtilis strain SY1483]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1090752 ACL6EQ_RS05260 WP_003245194.1 1033273..1033929(+) (mecA) [Bacillus subtilis strain SY1483]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment