Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACLMBL_RS05545 Genome accession   NZ_CP178536
Coordinates   1091645..1092331 (+) Length   228 a.a.
NCBI ID   WP_072361794.1    Uniprot ID   -
Organism   Staphylococcus aureus strain T144     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1086645..1097331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLMBL_RS05505 (ACLMBL_05505) yqeH 1086909..1088009 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  ACLMBL_RS05510 (ACLMBL_05510) - 1088039..1088272 (+) 234 Protein_1046 ribosome biogenesis GTPase YqeH -
  ACLMBL_RS05515 (ACLMBL_05515) aroE 1088286..1089092 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  ACLMBL_RS05520 (ACLMBL_05520) yhbY 1089096..1089386 (+) 291 WP_000627815.1 ribosome assembly RNA-binding protein YhbY -
  ACLMBL_RS05525 (ACLMBL_05525) nadD 1089389..1089958 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACLMBL_RS05530 (ACLMBL_05530) yqeK 1089948..1090532 (+) 585 WP_001019326.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACLMBL_RS05535 (ACLMBL_05535) rsfS 1090533..1090886 (+) 354 WP_001088020.1 ribosome silencing factor -
  ACLMBL_RS05540 (ACLMBL_05540) - 1090889..1091605 (+) 717 WP_117346056.1 class I SAM-dependent DNA methyltransferase -
  ACLMBL_RS05545 (ACLMBL_05545) comEA 1091645..1092331 (+) 687 WP_072361794.1 ComEA family DNA-binding protein Machinery gene
  ACLMBL_RS05550 (ACLMBL_05550) - 1092423..1092884 (+) 462 WP_000439693.1 ComE operon protein 2 -
  ACLMBL_RS05555 (ACLMBL_05555) comEC 1092889..1095090 (+) 2202 WP_025174327.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACLMBL_RS05560 (ACLMBL_05560) holA 1095147..1096121 (+) 975 WP_031587652.1 DNA polymerase III subunit delta -
  ACLMBL_RS05565 (ACLMBL_05565) rpsT 1096166..1096417 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1089971 ACLMBL_RS05545 WP_072361794.1 1091645..1092331(+) (comEA) [Staphylococcus aureus strain T144]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1089971 ACLMBL_RS05545 WP_072361794.1 1091645..1092331(+) (comEA) [Staphylococcus aureus strain T144]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.678

99.561

0.982
  comEA Staphylococcus aureus N315

97.797

99.561

0.974

Multiple sequence alignment