Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   ACL211_RS07485 Genome accession   NZ_CP178524
Coordinates   1607439..1608311 (-) Length   290 a.a.
NCBI ID   WP_002484839.1    Uniprot ID   A0A4Y7VXK4
Organism   Staphylococcus epidermidis strain X15T2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1568979..1639853 1607439..1608311 within 0


Gene organization within MGE regions


Location: 1568979..1639853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL211_RS07340 yfmF 1570019..1571290 (-) 1272 WP_002439538.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  ACL211_RS07345 - 1571321..1572034 (-) 714 WP_002439536.1 GntR family transcriptional regulator -
  ACL211_RS07350 - 1572037..1574430 (-) 2394 WP_049392165.1 DNA translocase FtsK -
  ACL211_RS07355 rnjB 1574696..1576369 (-) 1674 WP_002457357.1 ribonuclease J2 -
  ACL211_RS07360 pnp 1576737..1578842 (-) 2106 WP_001832554.1 polyribonucleotide nucleotidyltransferase -
  ACL211_RS07365 rpsO 1578974..1579243 (-) 270 WP_002439528.1 30S ribosomal protein S15 -
  ACL211_RS07370 - 1579363..1580334 (-) 972 WP_001832563.1 bifunctional riboflavin kinase/FAD synthetase -
  ACL211_RS07375 truB 1580350..1581267 (-) 918 WP_002456563.1 tRNA pseudouridine(55) synthase TruB -
  ACL211_RS07380 rbfA 1581405..1581755 (-) 351 WP_001829509.1 30S ribosome-binding factor RbfA -
  ACL211_RS07385 infB 1582058..1584220 (-) 2163 WP_002468903.1 translation initiation factor IF-2 -
  ACL211_RS07390 - 1584225..1584542 (-) 318 WP_002439520.1 YlxQ family RNA-binding protein -
  ACL211_RS07395 rnpM 1584542..1584826 (-) 285 WP_001829465.1 RNase P modulator RnpM -
  ACL211_RS07400 nusA 1584844..1586067 (-) 1224 WP_002456565.1 transcription termination factor NusA -
  ACL211_RS07405 rimP 1586088..1586555 (-) 468 WP_002439519.1 ribosome maturation factor RimP -
  ACL211_RS07410 - 1586734..1591044 (-) 4311 WP_002456566.1 PolC-type DNA polymerase III -
  ACL211_RS07415 - 1591294..1592997 (-) 1704 WP_001829513.1 proline--tRNA ligase -
  ACL211_RS07420 rseP 1593016..1594302 (-) 1287 WP_001829501.1 RIP metalloprotease RseP -
  ACL211_RS07425 - 1594536..1595318 (-) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  ACL211_RS07430 - 1595322..1596092 (-) 771 WP_001832561.1 isoprenyl transferase -
  ACL211_RS07435 frr 1596313..1596867 (-) 555 WP_001829472.1 ribosome recycling factor -
  ACL211_RS07440 pyrH 1596884..1597606 (-) 723 WP_002439511.1 UMP kinase -
  ACL211_RS07445 tsf 1597747..1598625 (-) 879 WP_002439509.1 translation elongation factor Ts -
  ACL211_RS07450 rpsB 1598777..1599565 (-) 789 WP_001832557.1 30S ribosomal protein S2 -
  ACL211_RS07455 codY 1599928..1600698 (-) 771 WP_002439506.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  ACL211_RS07460 hslU 1600722..1602125 (-) 1404 WP_001829474.1 ATP-dependent protease ATPase subunit HslU -
  ACL211_RS07465 hslV 1602194..1602736 (-) 543 WP_001829498.1 ATP-dependent protease subunit HslV -
  ACL211_RS07470 xerC 1602740..1603600 (-) 861 WP_002439503.1 tyrosine recombinase XerC -
  ACL211_RS07475 trmFO 1603855..1605162 (-) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  ACL211_RS07480 topA 1605187..1607256 (-) 2070 WP_001829508.1 type I DNA topoisomerase -
  ACL211_RS07485 dprA 1607439..1608311 (-) 873 WP_002484839.1 DNA-processing protein DprA Machinery gene
  ACL211_RS07490 sucD 1609116..1610024 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  ACL211_RS07495 sucC 1610046..1611212 (-) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  ACL211_RS07500 - 1611320..1612090 (-) 771 WP_001829514.1 ribonuclease HII -
  ACL211_RS07505 ylqF 1612095..1612958 (-) 864 WP_002468554.1 ribosome biogenesis GTPase YlqF -
  ACL211_RS07510 - 1613287..1615887 (+) 2601 WP_010959172.1 YfhO family protein -
  ACL211_RS07515 - 1615880..1618483 (+) 2604 WP_020368058.1 YfhO family protein -
  ACL211_RS07520 rplS 1619013..1619363 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  ACL211_RS07525 trmD 1619469..1620206 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  ACL211_RS07530 rimM 1620206..1620709 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  ACL211_RS07535 rpsP 1620836..1621111 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  ACL211_RS07540 ffh 1621419..1622786 (-) 1368 WP_001830113.1 signal recognition particle protein -
  ACL211_RS07545 - 1622817..1623149 (-) 333 WP_002457379.1 putative DNA-binding protein -
  ACL211_RS07550 ftsY 1623151..1624377 (-) 1227 WP_001830080.1 signal recognition particle-docking protein FtsY -
  ACL211_RS07555 smc 1624374..1627943 (-) 3570 WP_002502436.1 chromosome segregation protein SMC -
  ACL211_RS07560 rnc 1628070..1628807 (-) 738 WP_002470220.1 ribonuclease III -
  ACL211_RS07565 - 1628922..1629155 (-) 234 WP_001830184.1 acyl carrier protein -
  ACL211_RS07570 fabG 1629382..1630116 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  ACL211_RS07575 fabD 1630109..1631035 (-) 927 WP_001830062.1 ACP S-malonyltransferase -
  ACL211_RS07580 plsX 1631037..1632014 (-) 978 WP_001830112.1 phosphate acyltransferase PlsX -
  ACL211_RS07585 fapR 1632016..1632576 (-) 561 WP_001830099.1 transcription factor FapR -
  ACL211_RS07590 recG 1632735..1634783 (-) 2049 WP_020368084.1 ATP-dependent DNA helicase RecG -
  ACL211_RS07595 fakA 1634987..1636645 (-) 1659 WP_002489351.1 fatty acid kinase catalytic subunit FakA -
  ACL211_RS07600 - 1636660..1637034 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  ACL211_RS07605 rpmB 1637392..1637580 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  ACL211_RS07610 - 1637663..1638298 (-) 636 WP_002489340.1 thiamine diphosphokinase -
  ACL211_RS07615 rpe 1638303..1638947 (-) 645 WP_001830173.1 ribulose-phosphate 3-epimerase -
  ACL211_RS07620 rsgA 1638948..1639823 (-) 876 WP_002456227.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33717.61 Da        Isoelectric Point: 9.3616

>NTDB_id=1089880 ACL211_RS07485 WP_002484839.1 1607439..1608311(-) (dprA) [Staphylococcus epidermidis strain X15T2]
MIQQTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=1089880 ACL211_RS07485 WP_002484839.1 1607439..1608311(-) (dprA) [Staphylococcus epidermidis strain X15T2]
TTGATACAACAGACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y7VXK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566
  dprA Staphylococcus aureus N315

56.944

99.31

0.566

Multiple sequence alignment