Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   ACL211_RS00175 Genome accession   NZ_CP178524
Coordinates   40794..42143 (-) Length   449 a.a.
NCBI ID   WP_070863087.1    Uniprot ID   A0A2R3SZA6
Organism   Staphylococcus epidermidis strain X15T2     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 29838..48075 40794..42143 within 0


Gene organization within MGE regions


Location: 29838..48075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL211_RS00120 - 29838..30638 (+) 801 WP_001831758.1 MBL fold metallo-hydrolase -
  ACL211_RS00125 rlmH 31690..32169 (+) 480 WP_001831792.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACL211_RS00130 - 32283..33974 (+) 1692 WP_162195589.1 hypothetical protein -
  ACL211_RS00135 - 33961..34602 (+) 642 WP_162195588.1 hypothetical protein -
  ACL211_RS00140 - 34649..35464 (-) 816 WP_162195587.1 DNA-methyltransferase -
  ACL211_RS00145 - 35482..36522 (-) 1041 WP_162195586.1 DNA methyltransferase -
  ACL211_RS00150 - 36726..37216 (-) 491 Protein_27 DUF1643 domain-containing protein -
  ACL211_RS00155 - 37353..37856 (-) 504 WP_413226295.1 DUF1643 domain-containing protein -
  ACL211_RS00160 - 37871..38182 (-) 312 WP_162195584.1 DUF960 family protein -
  ACL211_RS00165 - 38269..38619 (-) 351 WP_162151871.1 SAUGI family uracil-DNA glycosylase inhibitor -
  ACL211_RS00170 ccrB 39144..40772 (-) 1629 WP_021758188.1 cassette chromosome recombinase CcrB Machinery gene
  ACL211_RS00175 ccrA 40794..42143 (-) 1350 WP_070863087.1 cassette chromosome recombinase CcrA Machinery gene
  ACL211_RS00180 cch1 42377..44164 (-) 1788 WP_232139946.1 cassette chromosome replicative helicase -
  ACL211_RS00185 ssb 44164..44454 (-) 291 WP_001656961.1 cassette chromosome ssDNA-binding protein -
  ACL211_RS00190 - 44609..45679 (+) 1071 WP_001656963.1 hypothetical protein -
  ACL211_RS00195 - 45773..47713 (+) 1941 WP_049281117.1 ATP-dependent DNA helicase -
  ACL211_RS00200 - 47893..48075 (-) 183 WP_002501913.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52643.32 Da        Isoelectric Point: 9.9585

>NTDB_id=1089857 ACL211_RS00175 WP_070863087.1 40794..42143(-) (ccrA) [Staphylococcus epidermidis strain X15T2]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLHQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1089857 ACL211_RS00175 WP_070863087.1 40794..42143(-) (ccrA) [Staphylococcus epidermidis strain X15T2]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATAAAATTATGTCAAACATATCGCGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATTATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTATGTGATTTCAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACATCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(169-248)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2R3SZA6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

98.218

100

0.982
  ccrA Staphylococcus aureus COL

74.61

100

0.746

Multiple sequence alignment