Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   ACLRDL_RS04160 Genome accession   NZ_CP178387
Coordinates   848984..849595 (-) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae isolate CTMA_1842     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 843984..854595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLRDL_RS04130 (ACLRDL_04130) tnpA 843991..844428 (+) 438 WP_317038486.1 IS200/IS605-like element IS1004 family transposase -
  ACLRDL_RS04135 (ACLRDL_04135) - 844512..845081 (-) 570 WP_000836327.1 BON domain-containing protein -
  ACLRDL_RS04140 (ACLRDL_04140) - 845084..845674 (-) 591 WP_000887295.1 phosphoheptose isomerase -
  ACLRDL_RS04145 (ACLRDL_04145) - 845678..846046 (-) 369 WP_001893625.1 YraN family protein -
  ACLRDL_RS04150 (ACLRDL_04150) - 846033..847838 (-) 1806 WP_001015478.1 penicillin-binding protein activator -
  ACLRDL_RS04155 (ACLRDL_04155) rsmI 847908..848774 (+) 867 WP_000131547.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  ACLRDL_RS04160 (ACLRDL_04160) hapR 848984..849595 (-) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  ACLRDL_RS04165 (ACLRDL_04165) hpt 849891..850424 (+) 534 WP_172778017.1 hypoxanthine phosphoribosyltransferase -
  ACLRDL_RS04170 (ACLRDL_04170) can 850499..851167 (-) 669 WP_001114111.1 carbonate dehydratase -
  ACLRDL_RS04175 (ACLRDL_04175) - 851315..852961 (+) 1647 WP_000484915.1 SulP family inorganic anion transporter -
  ACLRDL_RS04180 (ACLRDL_04180) - 853341..854258 (+) 918 WP_000271072.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=1089386 ACLRDL_RS04160 WP_000340100.1 848984..849595(-) (hapR) [Vibrio cholerae isolate CTMA_1842]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=1089386 ACLRDL_RS04160 WP_000340100.1 848984..849595(-) (hapR) [Vibrio cholerae isolate CTMA_1842]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCATT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCTGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAATTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment