Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACLNGX_RS14985 Genome accession   NZ_CP178374
Coordinates   3090905..3091549 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain 2023     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3085905..3096549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLNGX_RS14950 (ACLNGX_14950) - 3087090..3087521 (+) 432 WP_007408670.1 Na(+)/H(+) antiporter subunit B -
  ACLNGX_RS14955 (ACLNGX_14955) - 3087521..3087862 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  ACLNGX_RS14960 (ACLNGX_14960) - 3087855..3089336 (+) 1482 WP_412838365.1 Na+/H+ antiporter subunit D -
  ACLNGX_RS14965 (ACLNGX_14965) - 3089342..3089818 (+) 477 WP_007408672.1 Na+/H+ antiporter subunit E -
  ACLNGX_RS14970 (ACLNGX_14970) - 3089818..3090102 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  ACLNGX_RS14975 (ACLNGX_14975) mnhG 3090086..3090460 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  ACLNGX_RS14980 (ACLNGX_14980) - 3090500..3090883 (-) 384 WP_007408674.1 hotdog fold thioesterase -
  ACLNGX_RS14985 (ACLNGX_14985) comA 3090905..3091549 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  ACLNGX_RS14990 (ACLNGX_14990) comP 3091630..3093921 (-) 2292 WP_412838366.1 histidine kinase Regulator
  ACLNGX_RS14995 (ACLNGX_14995) comX 3093933..3094097 (-) 165 WP_007613432.1 competence pheromone ComX -
  ACLNGX_RS15000 (ACLNGX_15000) - 3094097..3095008 (-) 912 WP_031378407.1 polyprenyl synthetase family protein -
  ACLNGX_RS15005 (ACLNGX_15005) degQ 3095160..3095300 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACLNGX_RS15010 (ACLNGX_15010) - 3095765..3096106 (+) 342 WP_014305721.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=1089174 ACLNGX_RS14985 WP_003152052.1 3090905..3091549(-) (comA) [Bacillus velezensis strain 2023]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1089174 ACLNGX_RS14985 WP_003152052.1 3090905..3091549(-) (comA) [Bacillus velezensis strain 2023]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCAATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment